Lifeboat Foundation

(NEXSTAR) – A deadly fungus spreading in more than half of U.S. states is so concerning in part because of the way it has evolved to be resistant to both antimicrobial cleaning products and anti-fungal drugs, the Centers for Disease Control and Prevention recently warned.

The fungus, Candida auris or C. auris, has mainly spread in health care settings, like hospitals and nursing homes. Counterintuitively, because hospitals are disinfected so frequently, they can be the birthplace of bacteria or fungus that are resistant to cleaning products and to treatments.

What if we could just skip the workout part and take the results in supplement form? Researchers did it… On mice and flies.

Functional movement/conversion disorder (FMD), part of the spectrum of Functional Neurological Disorder (FND), is a neuropsychiatric condition marked by a range of neurological symptoms, including tremors, muscular spasms and cognitive difficulties. Despite being the second-most common cause of referrals to neurology outpatient clinics after headache, scientists have struggled to pin down the disorder’s root cause. Female sex and a history of childhood trauma are factors associated with higher risk of developing FMD, but it’s been unclear why.

A new study from investigators of the Brigham and Women’s Hospital, in collaboration with researchers at the National Institute of Neurological Disorders and Stroke, demonstrated that FMD is characterized by epigenetic changes, and that women and childhood abuse survivors with FMD have different epigenetic profiles linked to this condition. Their study, which examined the genomes of over 100 individuals and was recently published in Progress in Neuro-Psychopharmacology and Biological Psychiatry, is the first to demonstrate the occurrence of epigenetic changes in FMD.

“This study finally takes FMD out of a cloud of confusion and provides a neuroscientifically grounded explanation for why childhood trauma and female sex are associated with this disorder,” said lead author Primavera A. Spagnolo, MD, Ph.D., scientific director of the Mary Horrigan Connors Center for Women’s Health and Gender Biology and assistant professor of psychiatry at HMS.

On Earth Day 2023, we take a look at the state of the planet’s health. In Part 1, we assess the atmosphere.

In Part 1 of a two-part look at the state of Earth’s health, we look at changes in the planet’s atmosphere, both temperature and chemistry.

Experts from Charles River and Valo Health describe how artificial intelligence will change the drug discovery landscape.

The brain’s processing of reading is fascinating.

Reading is a fascinating process that engages many regions of our brain. We all know it’s an essential skill, but did you know that reading is like weightlifting for our minds? The more we read, the stronger our neural connections become, and the better we get at it. But what happens in our brains when we read? Scientists have been trying to answer this question for years, and a new study has finally shed some light on the matter.

A groundbreaking study led by neuroscientist Oscar Woolnough from the University of Texas Health Science Center at Houston shed new light on how our brains process language. According to the research, two distinct brain networks get activated while reading.

Findings point to brain areas that integrate planning, purpose, physiology, behavior, and movement.

Calm body, calm mind, say the practitioners of mindfulness. A new study by researchers at Washington University School of Medicine in St. Louis indicates that the idea that the body and mind are inextricably intertwined is more than just an abstraction. The study shows that parts of the brain area that control movement are plugged into networks involved in thinking and planning, and in control of involuntary bodily functions such as blood pressure and heartbeat. The findings represent a literal linkage of body and mind in the very structure of the brain.

The research, published on April 19 in the journal Nature, could help explain some baffling phenomena, such as why anxiety makes some people want to pace back and forth; why stimulating the vagus nerve, which regulates internal organ functions such as digestion and heart rate, may alleviate depression; and why people who exercise regularly report a more positive outlook on life.

In this episode, my guest is Matthew MacDougall, MD, the head neurosurgeon at Neuralink. Dr. MacDougall trained at the University of California, San Diego and Stanford University School of Medicine and is a world expert in brain stimulation, repair and augmentation. He explains Neuralink’s mission and projects to develop and use neural implant technologies and robotics to 1) restore normal movement to paralyzed patients and those with neurodegeneration-based movement disorders (e.g., Parkinson’s, Huntington’s Disease) and to repair malfunctions of deep brain circuitry (e.g., those involved in addiction). He also discusses Neuralink’s efforts to create novel brain-machine interfaces (BMI) that enhance human learning, cognition and communication as a means to accelerate human progress. Dr. MacDougall also explains other uses of bio-integrated machines in daily life; for instance, he implanted himself with a radio chip into his hand that allows him to open specific doors, collect and store data and communicate with machines and other objects in unique ways. Listeners will learn about brain health and function through the lens of neurosurgery, neurotechnology, clinical medicine and Neuralink’s bold and unique mission. Anyone interested in how the brain works and can be made to work better ought to derive value from this discussion.

#HubermanLab #Neuroscience.

Continue reading “Dr. Matthew MacDougall: Neuralink & Technologies to Enhance Human Brains | Huberman Lab Podcast” »

Magnetic resonance imaging (MRI) is how we visualize soft, watery tissue that is hard to image with X-rays. But while an MRI provides good enough resolution to spot a brain tumor, it needs to be a lot sharper to visualize microscopic details within the brain that reveal its organization.

In a decades-long technical tour de force led by Duke’s Center for In Vivo Microscopy with colleagues at the University of Tennessee Health Science Center, University of Pennsylvania, University of Pittsburgh and Indiana University, researchers took up the gauntlet and improved the resolution of MRI leading to the sharpest images ever captured of a mouse brain.

Continue reading “Brain images just got 64 million times sharper” »