Join a global community of lifelong learners with Big Think Get exclusive access to world-class ideas, members-only events, and conversations that challenge how you think, learn, and grow.
Sponsors: Accelerate your efficiency. Sign up for your one-dollar-per-month trial today at http://shopify.com/theories Sign up for Claude today at http://claude.ai/theoriesofeverything and checkout Claude Pro — which includes access to all of the features mentioned in today’s episode. I personally subscribe to The Economist. FLASH SALE to May 18: 50% off annual (double the usual!) No other podcast has this! https://economist.com/TOE
What if gravity is just entropy in disguise? Professor Erik Verlinde joins me to argue that gravity isn’t a fundamental force—it’s thermodynamic, emerging from quantum information the way gas pressure emerges from molecules bouncing around. We explore why spacetime may be stitched together by entanglement, and how dark energy and dark matter both pop out automatically without extra particles or parameters. Verlinde explains why the cosmological constant problem is a red herring, and why there may be no final theory of physics. When asked where the universe comes from, his answer is one word: chaos.
SUPPORT: Support me on Substack: https://curtjaimungal.substack.com/su… me on Crypto: https://commerce.coinbase.com/checkou… Support me on PayPal: https://www.paypal.com/donate?hosted_… JOIN MY SUBSTACK (Personal Writings): https://curtjaimungal.substack.com LISTEN ON SPOTIFY: https://open.spotify.com/show/4gL14b9… TIMESTAMPS:
LINKS MENTIONED: Papers, books, websites:
Videos:
SOCIALS:
Guests do not pay to appear. Theories of Everything receives revenue solely from viewer donations, platform ads, and clearly labelled sponsors; no guest or associated entity has ever given compensation, directly or through intermediaries. #science.
JOIN MY SUBSTACK (Personal Writings): https://curtjaimungal.substack.com.
LISTEN ON SPOTIFY: https://open.spotify.com/show/4gL14b9…
TIMESTAMPS: 00:00:00 — Thermodynamic Gravity and Information 00:06:35 — Beyond Effective Field Theory 00:13:08 — Turtles All The Way Down 00:25:41 — Entropy as a Force 00:36:31 — Entanglement and Spatial Connectivity 00:47:31 — Deriving Inertia and F=ma 00:56:41 — De Sitter Space Challenges 01:02:01 — Dark Matter and Milgram 01:11:51 — The Emergence of Time 01:21:01 — Statistical Gravity Fluctuations 01:27:01 — Quantum Computational Complexity 01:36:01 — Physics Intuition and Mentorship 01:47:31 — Beauty, Garbage, and Chaos.
The Moat: The moat is no longer how smart your AI is; it’s what your AI is allowed to touch. An agent that has “Write Access” to a company’s internal financial system or a medical record database is 100x more valuable than a “smart” chatbot that can only read public websites. Connectivity is the new Intellectual Property.
In the agentic economy, the most valuable human skill isn’t “coding” or “writing”—it is Agentic Orchestration.
The agentic economy thrives on Data Flywheels. As an agent performs a task (e.g., “Review this legal contract”), it gets human feedback (“This clause was too aggressive”). That feedback isn’t just a correction; it’s training data that makes the agent more valuable for the next task. This creates a winner-take-all dynamic for whoever has the most active agents in a specific niche.
We are moving toward an outcome-based economy. However, the real “gold rush” isn’t in building the smartest AI; it’s in building the safest and most connected AI—the one that humans trust enough to give the “keys” to their bank accounts, their calendars, and their businesses.
We proved that our Universe was made from AI Algorithm.
What if spacetime itself is the result of a gigantic self-learning quantum neural network? 🤯🌌
A new framework called the Universal Bridge Theorem (UBT) proposes a deep equivalence between:
🧠 Neural network training.
and.
🌌 The evolution of spacetime geometry.
The proposal combines:
Li et al. discovered that 4-octyl itaconate (4-OI) directly covalently modifies TYK2 and JAK1 to inhibit the type I interferon response. Endogenous metabolite itaconate in sepsis is a JAK inhibitor. In the mouse, in vivo experiments, intraperitoneal injection of 4-octyl itaconate could alleviate multi-organ damage caused by sepsis.
A multiplexed platform named NeuroSense enables near real-time monitoring of CSF biomarkers in patients in the neurological ICU, potentially supporting timelier diagnosis and intervention.
Read more in Science TranslationalMedicine.
NeuroSense enables near real-time, multimodal monitoring of external ventricular drains in neurocritical care.
Variant in situ sequencing (VIS-seq) links genetic variants to cell images, revealing how variants affect molecules, subcellular structures, and cells at scale. Applied to thousands of LMNA and PTEN variants, VIS-seq illuminated how variants impacted a multidimensional phenotypic continuum that is not recapitulated by any single functional readout.
Join the discord to participate in future comps! https://discord.gg/V5KFaF63mV
In this conversation, Lori Kirkland and Trey Simmons from Tamr, explore the transformative impact of AI on the workplace, emphasizing the importance of human-centric design and creativity. They discuss the acceleration of creative processes, the need for prioritization in business, and the shift in mindset required for organizations to thrive in an AI-driven world. The dialogue highlights the significance of collaboration, fluid thinking, and the evolving nature of business assumptions as key elements for future success. In this engaging conversation, Lori Kirkland and Trey Simmons explore essential human skills for the future, the mindset organizations need to adopt for the evolving workplace, and the profound nature of consciousness and reality. They discuss the impact of AI on our understanding of existence and the importance of fostering a culture of love and support in professional environments. The dialogue emphasizes the interconnectedness of humanity and the need for a shift in perspective to embrace change and innovation.
Connect with Trey via / treysimmons.
LETS CONNECT EVERYWHERE:
=============================
Instagram: / deephumanx.
LinkedIn: / deephumanx.
X (formerly Twitter): https://twitter.com/deephuman_x.
Facebook: / deephumanx.
DeepHumanX — Empowering Self Leadership in an AI Era.
https://www.deephumanx.com.
#wiredforwonder #selfleadership #futureofwork #businesspodcast #leadershipdevelopment #aiandhumans #emotionalintelligence #peoplefirst #businesssuccess #softskills #communicationmatters #employeeengagement #purposeatwork #leadershipskills #deephumanx.