Lifeboat Foundation

Humanity’s Michael Geer explains what Large Biological Models are and why they are the next giant leap in health.

Until now, it was not clear how hepatocytes were assigned tasks related to their localization. Researchers at the Spanish National Cancer Research Center (CNIO) have discovered that a gene, mTOR, is responsible for organizing the hepatocyte position map.

They also found that what triggers hepatocyte specialization is feeding after birth. The difference is marked by how nutrients reach the organism before and after birth: with no interruptions through the umbilical cord in one case, or in an intermittent fashion –when eating– in the other. The alternation of periods with and without available nutrients activates the mTOR gene and causes the hepatocytes to specialize, which completes the maturation of the liver.

Short version: You should be taking NAD boosters.

Professor Danica Chen from UC Berkeley presents ways to protect mitochondria and reverse stem cell aging in this video.
https://pubmed.ncbi.nlm.nih.gov/36255…
https://pubmed.ncbi.nlm.nih.gov/32504…
https://www.sciencedirect.com/science…
https://pubmed.ncbi.nlm.nih.gov/37146…
https://pubmed.ncbi.nlm.nih.gov/37919…

Continue reading “SIRTUINS 2, 3 & 7 PROTECT Mitochondria & REVERSE Stem Cell Aging!!!” »

ICYMI: March 15, 2024 was World Sleep Day.

Sleep is super important for the brain — that’s when memories can be turned from short term to long term memories. And during sleep the brain’s cleaning system is working at full capacity! 🫧🧼🚿💦

During sleep, our brains are busy consolidating memories and removing waste to keep our minds sharp. Recent findings from Yale on sleep hygiene and more.

NEW ORLEANS, March 18, 2024 — Doctors have long prescribed exercise to improve and protect health. In the future, a pill may offer some of the same benefits as exercise. Now, researchers report on new compounds that appear capable of mimicking the physical boost of working out — at least within rodent cells. This discovery could lead to a new way to treat muscle atrophy and other medical conditions in people, including heart failure and neurodegenerative disease.

The researchers will present their results today at the spring meeting of the American Chemical Society (ACS). ACS Spring 2024 is a hybrid meeting being held virtually and in person March 17–21; it features nearly 12,000 presentations on a range of science topics.

Continue reading “Mimicking exercise with a pill” »

An updated learning method—centered around walking, crouching, climbing, and jumping—could one day help the ANYmal robot vault over and crawl under physical hurdles during search and rescue missions.

The company’s long-lasting products may even help cut down on discarded food, around a third of which is tossed globally every year.

That waste then releases methane, a powerful heat-trapping gas, as it goes through the process of breaking down in landfills, contributing to rising global temperatures linked to extreme weather events that frequently cause displacement or damage vital food crops.

According to Packaging Digest, even though foodberries are perishable, they are safe and tasty to eat for anywhere from 60 to 90 days, though frozen items can last for more than a year.

EPFL’s BioRob team faced challenges field-testing bio-inspired robots in Uganda, leading to advancements and collaborations.

In a recent study published in The New England Journal of Medicine, a team of scientists from the United States (U.S.) and Canada evaluated the performance of a blood-based testing method that uses cell-free deoxyribonucleic acid (DNA) to screen for colorectal cancer.

Study: A Cell-free DNA Blood-Based Test for Colorectal Cancer Screening. Image Credit: Connect world/Shutterstock.com.