Lifeboat Foundation

In a new study in mice, a team of researchers from UCLA, the Swiss Federal Institute of Technology, and Harvard University have uncovered a crucial component for restoring functional activity after spinal cord injury. The neuroscientists have shown that re-growing specific neurons back to their natural target regions led to recovery, while random regrowth was not effective.

In a 2018 study published in Nature, the team identified a treatment approach that triggers axons —the tiny fibers that link nerve cells and enable them to communicate—to regrow after spinal cord injury in rodents. But even as that approach successfully led to the regeneration of axons across severe spinal cord lesions, achieving functional recovery remained a significant challenge.

Continue reading “Scientists regenerate neurons that restore walking in mice after paralysis from spinal cord injury” »

Generative artificial intelligence – the kind of AI behind the hugely popular ChatGPT application – already is disrupting the healthcare industry. C-suite executives and other health IT leaders at provider organizations need to know much to keep up and what to be wary of.

Venky Anant is a partner at research and consulting firm McKinsey Digital. He is our guest on this week’s podcast. He has vast expertise in AI and knows well its disruptive potential.

Learn more about the ways this disease travels to different parts of your body, and how treatment can help stop the spread.

The boundaries of science are constantly being pushed and expanded as newer and more advanced technology is developed, and researchers are now promising a “new era” of discovery as the world’s most powerful X-ray laser comes online.

The laser in question is the Linac Coherent Light Source (LCLS) II, and it’s able to produce up to a million X-ray flashes every single second. That’s some 8,000 times more than the original LCLS laser, creating a virtually continuous beam of highly energetic light that is 10,000 times brighter than before.

Continue reading “California Just Fired The World’s Most Powerful X-Ray Laser” »

“If you can get up to a watt per square meter, it would be very attractive from a cost perspective,” Assawaworrarit says.

The invention taps into a source of energy that’s easily overlooked

The Earth is constantly receiving a tremendous amount of energy from the Sun, to the tune of 173,000 terrawatts. Clouds, particles in the atmosphere, and reflective surfaces like snow-covered mountains immediately reflect 30 percent of that energy out into space. The rest of it ends up warming the land, oceans, clouds, atmosphere, and everything else on the planet.

In The Extended Mind: The Power of Thinking Outside the Brain (public library), Annie Murphy Paul explores the most thrilling frontiers of this growing understanding, fusing a century of scientific studies with millennia of first-hand experience from the lives and letters of great artists, scientists, inventors, and entrepreneurs. Challenging our cultural inheritance of thinking that thinking takes place only inside the brain, she illuminates the myriad ways in which we “use the world to think” — from the sensemaking language of gestures that we acquire as babies long before we can speak concepts to the singular fuel that time in nature provides for the brain’s most powerful associative network.

Paul distills this recalibration of understanding:

Thinking outside the brain means skillfully engaging entities external to our heads — the feelings and movements of our bodies, the physical spaces in which we learn and work, and the minds of the other people around us — drawing them into our own mental processes. By reaching beyond the brain to recruit these “extra-neural” resources, we are able to focus more intently, comprehend more deeply, and create more imaginatively — to entertain ideas that would be literally unthinkable by the brain alone.

Researchers from the Netherlands Institute for Neuroscience have, for the first time, witnessed nerve plasticity in the axon in motion.

Our nerve cells communicate through rapid transmission of electrical signals known as action potentials. All action potentials in the brain start in one unique small area of the cell: the axon initial segment (AIS). This is the very first part of the axon, the long, thin extension of a nerve cell that transmits signals or impulses from one nerve cell to another. It acts as a control center where it is decided when an action potential is initiated before traveling further along the axon.

Previously, researchers made the surprising observation that plasticity also occurs at the AIS. Plasticity refers to the brain’s ability to create new connections and structures in order to scale the amount of electrical activity, which is crucial for learning and memory. AIS plasticity occurs during changes in brain network activity.

The result: aspern Seestadt, reclaims a brownfield area to create a development that embraces new urban ideals while retaining the classical urban structure of old Vienna.

As aspern Seestadt has evolved, it has emerged as one of Europe’s most dynamic planned communities and an incubator for smart city initiatives. Geographic information system (GIS) technology helps planners implement clean energy and low-emission strategies and aids the long-range planning and implementation to ensure that aspern Seestadt achieves a unique balance of sustainability and livability.

-Vienna’s sustainable city within a city can be a model used by developing and developed countries dealing with housing crisis.

Continue reading “Inside One of Europe’s Largest Urban Development Projects—aspern Seestadt” »

PhonePe launched the Indus AppStore Developer Platform on Saturday, promising zero platform fee and no commission on in-app purchases as the Walmart-backed fintech races to win Android developers in Google’s largest market.

The Bengaluru-headquartered startup, which has amassed over 450 million registered users on its eponymous payments app, said developers can start registering and uploading their apps on the ‘made-in-India’ app store starting today. The app store, for which PhonePe has also partnered with phonemakers for distribution, features scores of locally relevant features including support for third-party payment providers, 12 Indian languages and a login system that revolves around phone numbers.

PhonePe will not charge developers any listing fee for the first year but move to a “nominal” cost thereafter, it said. The startup will additionally not levy a commission on in-app purchases, compared to Google’s 15–30% takerate. PhonePe, which leads the UPI-based payments market in India, said it has put in place an India-based team to offer support to developers, addressing the concerns of local developers who have been dissatisfied with Google’s delayed responses and U.S. timezone operating hours.