Lifeboat Foundation

Short version: One treated rat is sill alive and equivalent to a 110 year old human.

In this video we review the latest updates from Dr Katcher’s Lifespan trials and NEEL clinical trials.
NTZ Newsletter.
https://www.ntzplural.com/newsletter.
NEEL website.
https://www.neel.bio.

Continue reading “Dr Katcher’s E5 Experiment November 2022 Update” »

After statins, the next leading class of medications for managing cholesterol are PCSK9 inhibitors. These highly effective agents help the body pull excess cholesterol from the blood, but unlike statins, which are available as oral agents, PCSK9 inhibitors can only be administered as injections, creating barriers to their use.

Longevity. Technology: Having high cholesterol can increase the risk of heart and circulatory diseases such as heart attack, stroke and vascular dementia, but a new study from investigators at University Hospitals (UH) and Case Western Reserve University School of Medicine details an orally administered small-molecule drug that reduces PCSK9 levels and lowers cholesterol in animal models by 70%. Published in Cell Reports, the findings represent a previously unrecognised strategy for managing cholesterol and may also impact cancer treatments.

Cardiovascular disease ranking as the world’s number one killer, so it’s no surprise that a significant amount of research into potential therapeutic options is ongoing; just last week we looked at Cyclarity’s rationally-designed cyclodextrin molecules that remove arterial plaque by clearing the non-degradable oxidised cholesterol and which can be used in conjunction with statins for a broad-spectrum approach. Our report into Cyclarity’s new platform comes out next week, so stay tuned!

Research from the Babraham Institute has developed a method to “time jump” human skin cells by 30 years, turning back the aging clock for cells without losing their specialized function. Work by researchers in the Institute’s Epigenetics research program has been able to partly restore the function of older cells, as well as rejuvenating the molecular measures of biological age. The research is published today in the journal eLife, and while this topic is still at an early stage of exploration, it could revolutionize regenerative medicine.

What is regenerative medicine?

As we age, our cells’ ability to function declines and the genome accumulates marks of aging. Regenerative biology aims to repair or replace cells including old ones. One of the most important tools in regenerative biology is our ability to create “induced” stem cells. The process is a result of several steps, each erasing some of the marks that make cells specialized. In theory, these stem cells have the potential to become any cell type, but scientists aren’t yet able to reliably recreate the conditions to re-differentiate stem cells into all cell types.

Talk kindly contributed by Michael Levin in SEMF’s 2022 Spacious Spatiality.

https://semf.org.es/spatiality.

Continue reading “Michael Levin | Cell Intelligence in Physiological & Morphological Spaces” »

Dr. Dobri Kiprov about Therapeutic Plasma Exchange: New video from our 2022 #RejuvenationStartupSummit. Dobri is CSO at Lyfspn and an internationally renowned pioneer and expert in Therapeutic Apheresis, Immunotherapy, and Age-Related Disorders.

Enjoy -> https://lnkd.in/e_PZAsMm.

Continue reading “Dobri Kiprov at Rejuvenation Startup Summit 2022” »

The terms lifespan and longevity are often used interchangeably, which leads to much confusing and misinformation. Here we explore the difference between the two terms and why making a distinction is important.

The event, which was held at a luxury resort in the Swiss Alps last week, drew some of the world’s richest people along with some of its most controversial scientists.

Harvard Medical School genetics professor George Church, SENS Research Foundation chief of science offices Aubrey de Grey, Buck Institute for Research on Aging president and CEO Eric Verdin, Institute for Ageing Research at Albert Einstein College of Medicine director Nir Barzilai, Forever Healthy Foundation founder Michael Greve, Human Longevity Inc. associate professor, internal medicine Evelyne Yehudit Bischof, founder and CEO of Insilico Medicine Alex Zhavoronkov, creator of First Longevity and Longevity. Technology editor-in-chief Phil Newman, and Wei-Wu He, executive chairman of Human Longevity Inc., CEO and chairman of Casi Pharmaceuticals Inc., and founder and chairman of Genetron Health.

Continue reading “Billion-dollar meeting for the mega-rich who want to extend their lives” »

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TruDiagnostic Discount Link (Epigenetic Testing)
CONQUERAGING!
https://bit.ly/3Rken0n.

Continue reading “Epigenetic Test #3: What’s My Biological Age?” »

Researchers at Harvard University are investigating whether human genes could reverse the effects of aging. NBC Medical Fellow Dr. Akshay Syal got exclusive access to their lab to discuss the future of how to defy aging.

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Continue reading “Researchers Say They Are Close To Reversing Aging” »