Lifeboat Foundation

Researchers are working on water-based microprocessors that could one day be used as a more diverse alternative to the current wafer architecture of today, with applications ranging from AI to DNA synthesis and likely beyond.

The chips in question are still in the prototype stage, so don’t expect processors with built in water cooling just yet, but the way they work is really exciting. They use a technique called ionics, which involves manipulating different ion species in liquid, as opposed to the standard electrons shooting through our semiconductors today.

About Vladimir Putin

I did not write this song and I do not intend any copyright infringement.

Continue reading “Rush-The Weapon (Part II of Fear) (Lyrics)” »

A polariton condensate can spontaneously rotate, causing it to live significantly longer than individual polaritons would.

This is pioneering work for quantum teleportation as well making entanglement the main way for quantum teleportation communications in the future.

Award goes to three experimental physicists whose pioneering research has laid the groundwork for quantum information science.

Road-Haus by Wheelhaus challenges small-space cliches with high ceilings and oversize windows.

In the rapidly warming Eastern Mediterranean, water stratifies into layers, like a cake. That’s allowing carbon-spewing crystals to form.

Were you unable to attend Transform 2022? Check out all of the summit sessions in our on-demand library now! Watch here.

Microsoft Exchange server is one of those enterprise staples, but it’s also a key target for cybercriminals. Last week, GTSC reported attacks had begun chaining two new zero-day Exchange exploits as part of coordinated attacks.

While information is limited, Microsoft has confirmed in a blog post that these exploits have been used by a suspected state-sponsored threat actor to target fewer than 10 organizations and successfully exfiltrate data.

E to forgetting and false memories. However, if we believe that episodic memory developed to flexibly and creatively combine and rearrange memories of prior events in order to plan for the future, then it is quite a good system. We argue that consciousness originally developed as part of the episodic memory system—quite likely the part needed to accomplish that flexible recombining of information. We posit further that consciousness was subsequently co-opted to produce other functions that are not directly relevant to memory per se, such as problem-solving, abstract thinking, and language. We suggest that this theory is compatible with many phenomena, such as the slow speed and the after-the-fact order of consciousness, that cannot be explained well by other theories. We believe that our theory may have profound implications for understanding intentional action and consciousness in general. Moreover, we suggest that episodic memory and its associated memory systems of sensory, working, and semantic memory as a whole ought to be considered together as the conscious memory system in that they, together, give rise to the phenomenon of consciousness. Lastly, we suggest that the cerebral cortex is the part of the brain that makes consciousness possible, and that every cortical region contributes to this conscious memory system…

It is a commonly accepted view that light stimulation of mammalian photoreceptors causes a graded change in membrane potential instead of developing a spike. The presynaptic Ca²⁺ channels serve as a crucial link for the coding of membrane potential variations into neurotransmitter release. Ca_v1.4 L-type Ca²⁺ channels are expressed in photoreceptor terminals, but the complete pool of Ca²⁺ channels in cone photoreceptors appears to be more diverse. Here, we discovered, employing whole-cell patch-clamp recording from cone photoreceptor terminals in both sexes of mice, that their Ca²⁺ currents are composed of low-(T-type Ca²⁺ channels) and high-(L-type Ca²⁺ channels) voltage-activated components. Furthermore, Ca²⁺ channels exerted self-generated spike behavior in dark membrane potentials, and spikes were generated in response to light/dark transition. The application of fast and slow Ca²⁺ chelators revealed that T-type Ca²⁺ channels are located close to the release machinery. Furthermore, capacitance measurements indicated that they are involved in evoked vesicle release. Additionally, RT-PCR experiments showed the presence of Ca_v3.2 T-type Ca²⁺ channels in cone photoreceptors but not in rod photoreceptors. Altogether, we found several crucial functions of T-type Ca²⁺ channels, which increase the functional repertoire of cone photoreceptors. Namely, they extend cone photoreceptor light-responsive membrane potential range, amplify dark responses, generate spikes, increase intracellular Ca²⁺ levels, and boost synaptic transmission.

SIGNIFICANCE STATEMENT Photoreceptors provide the first synapse for coding light information. The key elements in synaptic transmission are the voltage-sensitive Ca²⁺ channels. Here, we provide evidence that mouse cone photoreceptors express low-voltage-activated Ca_v3.2 T-type Ca²⁺ channels in addition to high-voltage-activated L-type Ca²⁺ channels. The presence of T-type Ca²⁺ channels in cone photoreceptors appears to extend their light-responsive membrane potential range, amplify dark response, generate spikes, increase intracellular Ca²⁺ levels, and boost synaptic transmission. By these functions, Ca_v3.2 T-type Ca²⁺ channels increase the functional repertoire of cone photoreceptors.