Study shows #Glucagon is #Key for #Kidney #Health.
When researchers removed receptors for this hormone (best known for promoting blood sugar production in the liver) from mouse kidneys, the animals developed symptoms akin to chronic kidney disease…
Glucagon, a hormone best known for promoting blood sugar production in the liver, also appears to play a key role in maintaining kidney health. When UT Southwestern Medical Center researchers removed receptors for this hormone from mouse kidneys, the animals developed symptoms akin to chronic kidney disease (CKD).
Their findings, published in Cell Metabolism, shed new light on glucagon’s physiological functions and provide new insights into CKD, a disease that affects hundreds of millions of people around the globe, according to the National Institute of Diabetes and Digestive and Kidney Diseases.
“Our study defines important protective effects of glucagon for kidney health and normal systemic metabolic well-being of the entire organism,” said study leader Philipp Scherer, Ph.D., Professor of Internal Medicine and Cell Biology and Director of UTSW’s Touchstone Center for Diabetes Research.
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