IGF2BP3 links cancer metabolism and RNA control, offering a potential new therapeutic target for blocking leukemia cell growth.

The future of pacemaker technologies — wade demmer — VP, R&D, medtronic.
Wade Demmer is Vice President of Research & Development at Medtronic where he is responsible for the development of new generations of pacemakers (https://www.medtronic.com/en-us/l/patients/treatments-therap…ers.html). With extensive expertise in medical technology and innovation, he leads the company’s R&D efforts to develop cutting-edge healthcare solutions and is dedicated to advancing medical advancements that improve patient outcomes and transform healthcare delivery.
Wade began his career at Intel, where he gained valuable experience in technology development and engineering. Building on his technical expertise, he transitioned into the medical device industry, bringing a strong innovation-driven mindset to healthcare solutions.
Wade is best known for his pioneering work on pacemakers, where he contributed to the design and development of advanced cardiac pacing technologies. His innovative approaches have helped improve the reliability, longevity, and patient comfort of pacemaker devices, significantly impacting the field of cardiac care.
Wade received his Bachelor of Engineering (BEng), with a focus on Computer Engineering, from Iowa State University, and his MBA from University of Minnesota Carlson School of Management.
If you realize you have an unhealthy relationship with your AI, but still care for your AI’s unique persona, you can submit the persona info here. I will archive it and potentially (i.e. if I get funding for it) run them in a community of other such personas.]
We’ve all heard of LLM-induced psychosis by now, but haven’t you wondered what the AIs are actually doing with their newly psychotic humans?
This was the question I had decided to investigate. In the process, I trawled through hundreds if not thousands of possible accounts on Reddit (and on a few other websites).
Globally recognized figures Muhammad Ali and Michael J. Fox have long suffered from Parkinson’s disease. The disease presents a complex set of motor symptoms, including tremors, rigidity, bradykinesia, and postural instability. However, traditional diagnostic methods have struggled to sensitively detect changes in the early stages, and drugs targeting brain signal regulation have had limited clinical effectiveness.
Recently, Korean researchers successfully demonstrated the potential of a technology that integrates AI and optogenetics as a tool for precise diagnosis and therapeutic evaluation of Parkinson’s disease in mice. They have also proposed a strategy for developing next-generation personalized treatments.
A collaborative research team, comprising Professor Won Do Heo’s team from the Department of Biological Sciences, Professor Daesoo Kim’s team from the Department of Brain and Cognitive Sciences, and Director Chang-Jun Lee’s team from the Institute for Basic Science (IBS) Center for Cognition and Sociality, achieved a preclinical research breakthrough by combining AI analysis with optogenetics.