Dr. Prabha Sampath
Prabha
Sampath, Ph.D. is
Principal Investigator,
Institute of Medical Biology, A*Star, Singapore.
Trained at the Lerner Research Institute, Cleveland Clinic Foundation in
United States, Prabha studied gene regulation during
inflammation. She elucidated RNA and protein factors comprising major
pathways in inflammation. At the Center for Cardiovascular and
Regenerative Medicine, University of Washington, she investigated how a
network of translational regulators, control global and selective
protein synthesis during stem cell differentiation. This line of study
lead to new insights into translational control and stem cell
differentiation.
Prabha is currently pursuing research into post-transcriptional
regulation of stem cell differentiation, with a particular focus on its
relevance to neuronal and cardiac development. She is committed
to cutting-edge biomedical research and her innovative work is highly
recognized as evidenced by outstanding publications and multiple awards.
Her papers include
Regulated Release of L13a from the 60S Ribosomal
Subunit as A Mechanism of Transcript-Specific
Translational Control,
A Hierarchical Network Controls Protein
Translation during Murine Embryonic
Stem Cell Self-Renewal and Differentiation,
Transcript-Selective Translational Silencing by Gamma Interferon Is
Directed by a Novel Structural Element in the Ceruloplasmin mRNA
3' Untranslated Region,
Translational Control of Ceruloplasmin Gene Expression:
Beyond the IRE, and
Regulation of Macrophage Ceruloplasmin Gene Expression: One
Paradigm of 3'-UTR-mediated Translational Control.
Prabha is the recipient of a prestigious A*STAR Investigator award
(2007), and she joined the IMB to set up her own research group in May
2008.
Read
Potential drug for deadly brain cancer.
Read her
LinkedIn profile.