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Dr. Luigi Ferrucci

Luigi Ferrucci, M.D., Ph.D. is the Scientific Director and Senior Investigator at the National Institute on Aging at the National Institute of Health. He is a Geriatrician and Epidemiologist who researches the causal pathways leading to progressive physical and cognitive decline in older persons.

He is also a highly-rated General Practice Doctor in Baltimore, Maryland in more than 22 conditions. His top areas of expertise are Peripheral Artery Disease, Dementia, Atherosclerosis, Alzheimer’s Disease, and Hormone Replacement Therapy (HRT).

Luigi has been Scientific Director at NIA since May 2011. In September 2002, he became the Chief of the Longitudinal Studies Section at NIA and the Director of the Baltimore Longitudinal Study on Aging. Read A valuable data resource: Baltimore Longitudinal Study of Aging, A ‘dream team’ collaboration on cancer in aging, and A new CARD to play in the battle against Alzheimer’s and related dementias.

Luigi is the Principal Investigator in the Intramural Research Program (IRP). This is the internal research program of the National Institutes of Health (NIH), known for its synergistic approach to biomedical science. With approximately 1,200 Principal Investigators and more than 4,000 Postdoctoral Fellows conducting basic, translational, and clinical research, the IRP is the largest biomedical research institution on earth.

Luigi earned his Medical Degree and Board Certification in 1980, a Board Certification in Geriatrics in 1982, and Ph.D. in Biology and Pathophysiology of Aging in 1998 at the University of Florence, Italy.

Between 1985 and 2002, he was Chief of Geriatric Rehabilitation at the Department of Geriatric Medicine and Director of the Laboratory of Clinical Epidemiology at the Italian National Institute of Aging. During the same period, he collaborated with the NIA Laboratory of Epidemiology, Demography, and Biometry where he spent several periods as Visiting Scientist at NIH.

Luigi has made major contributions to the design of many epidemiological studies conducted in the U.S. and Europe, including the AKEA study of Centenarians in Sardinia and the Women’s Health and Aging Study.

He was also the Principal Investigator of the InCHIANTI study, a longitudinal study conducted in the Chianti Geographical area (Tuscany, Italy) looking at risk factors for mobility disability in older persons.

In 2002, Luigi refined the design of the Baltimore Longitudinal Study of Aging to focus on the Geroscience Hypothesis, which states that the pace of biological aging is the root cause of many age-related chronic diseases and physical and cognitive disability. He has made major contributions to the literature and is one of the most cited scientists in the field of aging.

He is a Scientific Board Member of the X-Prize, a member of the Live Forever Club, and was invited Speaker at many conferences and symposiums, among others at Santa Fe Group’s Continuum on Benefits of Integrating Oral Health into Overall Health, Targeting Metabesity 2022, Research on the ageing phenotypes: toward a translational perspective 2014, ARDD 2021 – 8th Aging Research and Drug Discovery Meeting, ARDD 2023 – 10th Aging Research & Drug Discovery Meeting, and Aging Research Day Conference 2024.

Luigi was also an Investigator at the NIH Post-Infectious ME/CFS Study. They did an extensive study of 40 patients with “PI-ME/CFS” (Post-Infectious ME/CFS) to define subgroups of ME/CFS, find diagnostic biomarkers, and identify treatments.

Watch EuGMS 2023 – Satellite Symposium. Innovative Ways to Support Mobility into Old Age: An Interconnected Musculoskeletal Strategy, Research on Aging and Age-Related Diseases, VitaDAO – Funding Aging Research with Dr. Luigi Ferrucci NIH-NIA Director, Luigi Ferrucci – International Symposium “Multimorbidity research at the cross-roads”, and The secrets of healthy aging.

Listen to News and interview with Dr. Luigi Ferrucci, NIH Institute on Aging, Bethesda, MD, Early Legislative Actions, Implement Data Systems Now, and Dr. Luigi Ferrucci on improving care of older patients with complex multimorbidity and frailty.

Read The Cost Of Unhealthy Aging and Frailty in real life and its translational implications. Read The National Institute on Aging’s Luigi Ferrucci, MD, PhD receives the IOA’s 2016 Joseph A. Pignolo Award in Aging Research.

Visit his Work page, PubMed page, and LinkedIn profile. Follow him on Google Scholar, Facebook, and Twitter.