Advisory Board

Professor John F. Peroni

The Daily Mail article Revolutionary putty could heal bone fractures in days rather than months, claim scientists said

Anyone who has broken a bone knows how long and arduous the recovery period can be.
 
Now scientists say they have created a revolutionary “putty” that can put the healing process into super-drive.
 
Scientists from the University of Georgia Regenerative Bioscience Center used adult stem cells to produce a protein involved in bone healing and generation.
 
They then incorporated them into a gel, combining the healing properties into something they labelled “fracture putty”.
 
Working with Dr John Peroni from the UGA College of Veterinary Medicine the team used a stabilizing device and inserted putty into fractures in rats.

John F. Peroni, DVM, MS, Dip ACVS is Associate Professor of Large Animal Surgery, College of Veterinary Medicine, University of Georgia and is Chairman of the North American Veterinary Regenerative Medicine Association (NAVRMA).
 
As a clinician, John has treated a number of horses with musculoskeletal problems amenable to regenerative approaches including mesenchymal stem cells (MSCs) and platelet-rich plasma. He has focused on the use of transduced MSCs in bone formation using an ovine fracture model, as well as the immunomodulatory effects of equine bone marrow-derived MSCs as part of an investigation into the use of allogenic stem cells for therapeutic purposes.
 
His research includes the development of immune responses following exposure of equine lymphocytes and monocytes to allogenic MSCs in attempt to understand the relations between these cells and the immune system.
 
His papers include Predisposition for venoconstriction in the equine laminar dermis: implications in equine laminitis, Effects of induction of capacitative calcium entry on equine laminar microvessels, Evaluation of a cranial arthroscopic approach to the stifle joint for the treatment of femorotibial joint disease in horses: 23 cases (1998–1999), Equine laminitis: A journey to the dark side of venous, Evaluation of activation of protein kinase C during agonist-induced constriction of veins isolated from the laminar dermis of horses, Thoracoscopy in horses, How to Apply a Bioresorbable Hyaluronate Membrane for the Prevention of Postoperative Adhesions in Horses, and Rapid Heterotrophic Ossification with Cryopreserved Poly(ethylene glycol-)Microencapsulated BMP2-Expressing MSCs.