Dr. Prabha Sampath
Sampath, Ph.D. is
Institute of Medical Biology, A*Star, Singapore.
Trained at the Lerner Research Institute, Cleveland Clinic Foundation in United States, Prabha studied gene regulation during inflammation. She elucidated RNA and protein factors comprising major pathways in inflammation. At the Center for Cardiovascular and Regenerative Medicine, University of Washington, she investigated how a network of translational regulators, control global and selective protein synthesis during stem cell differentiation. This line of study lead to new insights into translational control and stem cell differentiation.
Prabha is currently pursuing research into post-transcriptional regulation of stem cell differentiation, with a particular focus on its relevance to neuronal and cardiac development. She is committed to cutting-edge biomedical research and her innovative work is highly recognized as evidenced by outstanding publications and multiple awards.
Her papers include Regulated Release of L13a from the 60S Ribosomal Subunit as A Mechanism of Transcript-Specific Translational Control, A Hierarchical Network Controls Protein Translation during Murine Embryonic Stem Cell Self-Renewal and Differentiation, Transcript-Selective Translational Silencing by Gamma Interferon Is Directed by a Novel Structural Element in the Ceruloplasmin mRNA 3' Untranslated Region, Translational Control of Ceruloplasmin Gene Expression: Beyond the IRE, and Regulation of Macrophage Ceruloplasmin Gene Expression: One Paradigm of 3'-UTR-mediated Translational Control.
Prabha is the recipient of a prestigious A*STAR Investigator award (2007), and she joined the IMB to set up her own research group in May 2008.
Read Potential drug for deadly brain cancer. Read her LinkedIn profile.