Professor Ennio Tasciotti

Ennio Tasciotti, Ph.D. is Assistant Professor, Division of Nanomedicine, Institute of Molecular Medicine (IMM), University of Texas at Houston, Houston, Texas.
 
Despite extraordinary progress in the laboratory, cancer mortality has not been reduced by any significant amount in the last fifty years. The main reasons are that "cancer" is actually several hundreds of disease, which differ dramatically in terms of their biology, and respond very differently to drugs.
 
Ennio believes that nanotechnology offers unprecedented opportunities to develop minimally invasive, economically feasible approaches to early detection and treatment of cancer with the ultimate goal of achieving the personalization of intervention. His interests are in the field of drug delivery for cancer treatment and in the field of early diagnosis of tumor burden through protein profiling in the blood.
 
He coauthored Novel human-derived cell-penetrating peptides for specific subcellular delivery of therapeutic biomolecules, Transcellular transfer of active HSV-1 thymidine kinase mediated by an 11-amino-acid peptide from HIV-1 Tat, Mesoporous silicon particles as a multistage delivery system for imaging and therapeutic applications, In Vivo Imaging Shows Abnormal Function of Vascular Endothelial Growth Factor-Induced Vasculature, Fusion of the Human Immunodeficiency Virus Type 1 Tat Protein Transduction Domain to Thymidine Kinase Increases Bystander Effect and Induces Enhanced Tumor Killing In Vivo, and Nanotechnology for breast cancer therapy. His patent applications include Multistage Delivery of Active Agents.
 
Ennio earned his MSc in Biological Sciences at the University of Pisa, Italy in 2000. He earned his MSc in Molecular Biology at Scuola Normale Superiore Pisa, Italy, 2000. He earned his Ph.D. in Molecular Medicine at Scuola Normale Superiore Pisa, Italy, in 2005. He did his Postdoc work at the International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy and at the University of Texas Health Science Center at Houston, Houston, Texas.
 
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