{"id":99956,"date":"2019-12-19T22:47:01","date_gmt":"2019-12-20T06:47:01","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2019\/12\/inflammation-marker-may-be-a-red-flag-for-rapid-brain-aging"},"modified":"2019-12-19T22:47:01","modified_gmt":"2019-12-20T06:47:01","slug":"inflammation-marker-may-be-a-red-flag-for-rapid-brain-aging","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2019\/12\/inflammation-marker-may-be-a-red-flag-for-rapid-brain-aging","title":{"rendered":"Inflammation Marker May Be a Red Flag for Rapid Brain Aging"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/inflammation-marker-may-be-a-red-flag-for-rapid-brain-aging.jpg\"><\/a><\/p>\n<p>This study involved 4,717 participants from two different community-based cohorts. A meta-analysis of both cohorts showed that elevated sCD14 was associated with a 12 percent increased risk of dementia as people got older. Higher levels of sCD14 were also associated with accelerated brain aging in both cohorts, a faster progression of age-related brain atrophy, and a more rapid decline of executive functions.<\/p>\n<p>The authors sum up their findings: \u201csCD14 is an inflammatory marker related to brain atrophy, cognitive decline, and incident dementia.\u201d<\/p>\n<p>\u201cHigher levels of sCD14 were associated with markers of brain aging and injury, such as total brain atrophy and a decline in executive functioning\u2014the <a href=\"https:\/\/www.psychologytoday.com\/us\/basics\/decision-making\" class=\"\" title=\"Psychology Today looks at decision-making\">decision-making<\/a> needed for many activities of daily life,\u201d first author <a href=\"https:\/\/www.florey.edu.au\/science-research\/scientist-directory\/dr-matthew-pase\">Matthew Pase<\/a>, of the Florey Institute for Neuroscience and Mental Health in Melbourne, Australia, said in a news release.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This study involved 4,717 participants from two different community-based cohorts. A meta-analysis of both cohorts showed that elevated sCD14 was associated with a 12 percent increased risk of dementia as people got older. Higher levels of sCD14 were also associated with accelerated brain aging in both cohorts, a faster progression of age-related brain atrophy, and [\u2026]<\/p>\n","protected":false},"author":511,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[269,47],"tags":[],"class_list":["post-99956","post","type-post","status-publish","format-standard","hentry","category-life-extension","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/99956","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/511"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=99956"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/99956\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=99956"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=99956"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=99956"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}