{"id":99873,"date":"2019-12-17T19:44:50","date_gmt":"2019-12-18T03:44:50","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2019\/12\/new-tool-reveals-dna-structures-that-influence-disease"},"modified":"2019-12-17T19:44:50","modified_gmt":"2019-12-18T03:44:50","slug":"new-tool-reveals-dna-structures-that-influence-disease","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2019\/12\/new-tool-reveals-dna-structures-that-influence-disease","title":{"rendered":"New tool reveals DNA structures that influence disease"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/new-tool-reveals-dna-structures-that-influence-disease2.jpg\"><\/a><\/p>\n<p>Disruption of certain DNA structures\u2014called topologically associating domains, or TADs\u2014is linked with the development of disease, including some cancers. With its newly created algorithm that quickly locates and helps elucidate the complex functions of TADs, an international team of researchers is making it easier to study these important structures and help prevent disease.<\/p>\n<p>\u201cOn your DNA you have <a href=\"https:\/\/phys.org\/tags\/genes\/\" rel=\"tag\" class=\"\">genes<\/a> and regulatory elements\u2014such as promotors and enhancers\u2014that <a href=\"https:\/\/phys.org\/tags\/control+gene+expression\/\" rel=\"tag\" class=\"\">control gene expression<\/a>, but these two things can be far away from each other,\u201d said Qunhua Li, associate professor of statistics, Penn State. \u201cSimilar to a dresser drawer that keeps your clothes organized and available for use, TADs bring genes together with their regulatory elements, which enables them to begin the process of gene expression.\u201d<\/p>\n<p>Gene expression is the process by which the information encoded in DNA gives rise to observable traits.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Disruption of certain DNA structures\u2014called topologically associating domains, or TADs\u2014is linked with the development of disease, including some cancers. With its newly created algorithm that quickly locates and helps elucidate the complex functions of TADs, an international team of researchers is making it easier to study these important structures and help prevent disease. \u201cOn your [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,41],"tags":[],"class_list":["post-99873","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-information-science"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/99873","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=99873"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/99873\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=99873"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=99873"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=99873"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}