{"id":99852,"date":"2019-12-17T14:43:21","date_gmt":"2019-12-17T22:43:21","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2019\/12\/the-first-evidence-that-drugs-could-turn-back-the-clock-on-our-biological-age"},"modified":"2019-12-17T14:43:21","modified_gmt":"2019-12-17T22:43:21","slug":"the-first-evidence-that-drugs-could-turn-back-the-clock-on-our-biological-age","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2019\/12\/the-first-evidence-that-drugs-could-turn-back-the-clock-on-our-biological-age","title":{"rendered":"The First Evidence That Drugs Could Turn Back the Clock on Our Biological Age"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/the-first-evidence-that-drugs-could-turn-back-the-clock-on-our-biological-age3.jpg\"><\/a><\/p>\n<p>After decades of research, here it is: the <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1111\/acel.13028\">first promising evidence<\/a> in humans, albeit imperfect and early, that a cocktail of three drugs is enough to reverse the epigenetic clock\u2014a measure of someone\u2019s biological age and health.<\/p>\n<p>The results came as a surprise to even the research team, who originally designed the trial for something a little less dazzling: to look at human growth hormone\u2019s effects on the <a href=\"https:\/\/en.wikipedia.org\/wiki\/Thymus\">thymus<\/a>, the cradle of the body\u2019s immune system that deteriorates with age.<\/p>\n<p>\u201cMaintained immune function is seen in centenarians,\u201d and thymus function is linked to all-cause mortality, <a href=\"https:\/\/www.nature.com\/articles\/d41586-019-02638-w\">explained<\/a> study author Dr. Gregory Fahy at Intervene Immune, based in Los Angeles, California. \u201cSo we were hoping to use a year of growth hormone to maintain thymus function in middle-aged men, right before the tissue\u2019s functions take a nosedive,\u201d he said.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>After decades of research, here it is: the first promising evidence in humans, albeit imperfect and early, that a cocktail of three drugs is enough to reverse the epigenetic clock\u2014a measure of someone\u2019s biological age and health. The results came as a surprise to even the research team, who originally designed the trial for something [\u2026]<\/p>\n","protected":false},"author":511,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,269],"tags":[],"class_list":["post-99852","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/99852","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/511"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=99852"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/99852\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=99852"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=99852"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=99852"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}