{"id":99404,"date":"2019-12-06T16:23:12","date_gmt":"2019-12-07T00:23:12","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2019\/12\/researchers-program-cancer-fighting-cells-to-resist-exhaustion-attack-solid-tumors-in-mice"},"modified":"2019-12-06T16:23:12","modified_gmt":"2019-12-07T00:23:12","slug":"researchers-program-cancer-fighting-cells-to-resist-exhaustion-attack-solid-tumors-in-mice","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2019\/12\/researchers-program-cancer-fighting-cells-to-resist-exhaustion-attack-solid-tumors-in-mice","title":{"rendered":"Researchers program cancer-fighting cells to resist exhaustion, attack solid tumors in mice"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/researchers-program-cancer-fighting-cells-to-resist-exhaustion-attack-solid-tumors-in-mice2.jpg\"><\/a><\/p>\n<p>Awesome!<\/p>\n<hr>\n<p>A new approach to programing cancer-fighting immune cells called CAR-T cells can prolong their activity and increase their effectiveness against human cancer cells grown in the laboratory and in mice, according to a study by researchers at the Stanford University School of Medicine.<\/p>\n<p>The ability to circumvent the exhaustion that the genetically engineered cells often experience after their initial burst of activity could lead to the development of a new generation of CAR-T cells that may be effective even against solid cancers\u2014a goal that has until now eluded researchers.<\/p>\n<p>The studies were conducted in mice harboring human leukemia and <a href=\"https:\/\/medicalxpress.com\/tags\/bone+cancer+cells\/\" rel=\"tag\" class=\"\">bone cancer cells<\/a>. The researchers hope to begin <a href=\"https:\/\/medicalxpress.com\/tags\/clinical+trials\/\" rel=\"tag\" class=\"\">clinical trials<\/a> in people with leukemia within the next 18 months and to eventually extend the trials to include solid cancers.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Awesome! A new approach to programing cancer-fighting immune cells called CAR-T cells can prolong their activity and increase their effectiveness against human cancer cells grown in the laboratory and in mice, according to a study by researchers at the Stanford University School of Medicine. The ability to circumvent the exhaustion that the genetically engineered cells [\u2026]<\/p>\n","protected":false},"author":511,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-99404","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/99404","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/511"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=99404"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/99404\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=99404"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=99404"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=99404"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}