{"id":99137,"date":"2019-11-29T06:42:54","date_gmt":"2019-11-29T14:42:54","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2019\/11\/swiss-army-knife-for-genome-research"},"modified":"2019-12-09T01:39:13","modified_gmt":"2019-12-09T09:39:13","slug":"swiss-army-knife-for-genome-research","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2019\/11\/swiss-army-knife-for-genome-research","title":{"rendered":"Swiss army knife for genome research"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/swiss-army-knife-for-genome-research2.jpg\"><\/a><\/p>\n<p>It is the dream of every molecular geneticist: an easy-to-use program that compares datasets from different cellular conditions, identifies enhancer regions and then assigns them to their target genes. A research team led by Martin Vingron at the Max Planck Institute for Molecular Genetics in Berlin has now developed a program that does all of this.<\/p>\n<p>\u201cDNA is pretty boring, since it is practically the same in every cell,\u201d says Martin Vingron, director and head of the Department of Bioinformatics at the Max Planck Institute for Molecular Genetics in Berlin. \u201cWhile the genome is like the book of life, I am most interested in the side notes.\u201d<\/p>\n<p>These \u201cnotes\u201d are small chemical marks attached to the DNA molecule that do not alter the genetic information itself, but influence what happens to the DNA at the respective site. In other words, these marks have an epigenetic effect. They serve as regulators of genomic regions that are responsible for the activation and deactivation of <a href=\"https:\/\/phys.org\/tags\/genes\/\" rel=\"tag\" class=\"\">genes<\/a>, such as promoters and enhancers.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>It is the dream of every molecular geneticist: an easy-to-use program that compares datasets from different cellular conditions, identifies enhancer regions and then assigns them to their target genes. A research team led by Martin Vingron at the Max Planck Institute for Molecular Genetics in Berlin has now developed a program that does all of [\u2026]<\/p>\n","protected":false},"author":513,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-99137","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/99137","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/513"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=99137"}],"version-history":[{"count":1,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/99137\/revisions"}],"predecessor-version":[{"id":99495,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/99137\/revisions\/99495"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=99137"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=99137"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=99137"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}