{"id":98277,"date":"2019-11-08T08:22:31","date_gmt":"2019-11-08T16:22:31","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2019\/11\/modified-crispr-gene-editing-tool-could-improve-therapies-for-hiv-sickle-cell-disease"},"modified":"2019-11-08T08:22:31","modified_gmt":"2019-11-08T16:22:31","slug":"modified-crispr-gene-editing-tool-could-improve-therapies-for-hiv-sickle-cell-disease","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2019\/11\/modified-crispr-gene-editing-tool-could-improve-therapies-for-hiv-sickle-cell-disease","title":{"rendered":"Modified CRISPR gene editing tool could improve therapies for HIV, sickle cell disease"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/modified-crispr-gene-editing-tool-could-improve-therapies-for-hiv-sickle-cell-disease2.jpg\"><\/a><\/p>\n<p>City of Hope researchers may have found a way to sharpen the fastest, cheapest and most accurate gene editing technique, CRISPR-Cas9, so that it can more successfully cut out undesirable genetic information.<\/p>\n<p>This improved cutting ability could one day fast-track potential therapies for HIV, <a href=\"https:\/\/phys.org\/tags\/sickle+cell+disease\/\" rel=\"tag\" class=\"\">sickle cell disease<\/a> and, potentially, other immune conditions.<\/p>\n<p>\u201cOur CRISPR-Cas9 design may be the difference between trying to cut a ribeye steak with a butter knife versus slicing it with a steak knife,\u201d said Tristan Scott, Ph.D., lead author of the study and a staff research scientist at City of Hope\u2019s Center for Gene Therapy. \u201cOther scientists have tried to improve CRISPR cutting through chemical modifications, but that\u2019s an expensive process and is like diamond-coating a blade. Instead, we have designed a better pair of scissors you can buy at any convenience store.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>City of Hope researchers may have found a way to sharpen the fastest, cheapest and most accurate gene editing technique, CRISPR-Cas9, so that it can more successfully cut out undesirable genetic information. This improved cutting ability could one day fast-track potential therapies for HIV, sickle cell disease and, potentially, other immune conditions. \u201cOur CRISPR-Cas9 design [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,412],"tags":[],"class_list":["post-98277","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/98277","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=98277"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/98277\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=98277"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=98277"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=98277"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}