{"id":98240,"date":"2019-11-07T13:23:20","date_gmt":"2019-11-07T21:23:20","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2019\/11\/first-use-of-crispr-against-cancer-in-patients-clears-safety-hurdles"},"modified":"2019-11-07T13:23:20","modified_gmt":"2019-11-07T21:23:20","slug":"first-use-of-crispr-against-cancer-in-patients-clears-safety-hurdles","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2019\/11\/first-use-of-crispr-against-cancer-in-patients-clears-safety-hurdles","title":{"rendered":"First use of CRISPR against cancer in patients clears safety hurdles"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/first-use-of-crispr-against-cancer-in-patients-clears-safety-hurdles3.jpg\"><\/a><\/p>\n<p>The first attempt in the United States to use a gene editing tool called CRISPR against cancer seems safe in the three patients who have had it so far, but it\u2019s too soon to know if it will improve survival, doctors reported Wednesday.<\/p>\n<p>The doctors were able to take immune system cells from the patients\u2019 blood and alter them genetically to help them recognize and fight cancer, with minimal and manageable side effects. The treatment deletes three genes that might have been hindering these cells\u2019 ability to attack the disease, and adds a new, fourth feature to help them do the job.<\/p>\n<p>\u201cIt\u2019s the most complicated genetic, cellular engineering that\u2019s been attempted so far,\u201d said the study leader, Dr. Edward Stadtmauer of the University of Pennsylvania in Philadelphia. \u201cThis is proof that we can safely do gene editing of these cells.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The first attempt in the United States to use a gene editing tool called CRISPR against cancer seems safe in the three patients who have had it so far, but it\u2019s too soon to know if it will improve survival, doctors reported Wednesday. The doctors were able to take immune system cells from the patients\u2019 [\u2026]<\/p>\n","protected":false},"author":511,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,412],"tags":[],"class_list":["post-98240","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/98240","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/511"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=98240"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/98240\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=98240"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=98240"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=98240"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}