{"id":95292,"date":"2019-08-25T22:03:15","date_gmt":"2019-08-26T05:03:15","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2019\/08\/a-novel-technology-for-genome-editing-a-broad-range-of-mutations-in-live-organisms"},"modified":"2019-08-25T22:03:15","modified_gmt":"2019-08-26T05:03:15","slug":"a-novel-technology-for-genome-editing-a-broad-range-of-mutations-in-live-organisms","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2019\/08\/a-novel-technology-for-genome-editing-a-broad-range-of-mutations-in-live-organisms","title":{"rendered":"A novel technology for genome-editing a broad range of mutations in live organisms"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/a-novel-technology-for-genome-editing-a-broad-range-of-mutations-in-live-organisms.jpg\"><\/a><\/p>\n<p>The ability to edit genes in living organisms offers the opportunity to treat a plethora of inherited diseases. However, many types of gene-editing tools are unable to target critical areas of DNA, and creating such a technology has been difficult as living tissue contains diverse types of cells.<\/p>\n<p>Now, Salk Institute researchers have developed a new tool\u2014dubbed SATI\u2014to edit the <a href=\"https:\/\/phys.org\/tags\/mouse+genome\/\" rel=\"tag\" class=\"\">mouse genome<\/a>, enabling the team to target a broad range of mutations and cell types. The new genome-editing technology, described in <i>Cell Research<\/i> on August 23, 2019, could be expanded for use in a broad range of gene mutation conditions such as Huntington\u2019s disease and the rare premature aging syndrome, progeria.<\/p>\n<p>\u201cThis study has shown that SATI is a powerful tool for genome editing,\u201d says Juan Carlos Izpisua Belmonte, a professor in Salk\u2019s Gene Expression Laboratory and senior author of the paper. \u201cIt could prove instrumental in developing effective strategies for target-gene replacement of many different types of mutations, and opens the door for using genome-editing tools to possibly cure a broad range of genetic diseases.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The ability to edit genes in living organisms offers the opportunity to treat a plethora of inherited diseases. However, many types of gene-editing tools are unable to target critical areas of DNA, and creating such a technology has been difficult as living tissue contains diverse types of cells. Now, Salk Institute researchers have developed a [\u2026]<\/p>\n","protected":false},"author":511,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,269],"tags":[],"class_list":["post-95292","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/95292","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/511"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=95292"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/95292\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=95292"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=95292"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=95292"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}