{"id":94861,"date":"2019-08-16T10:02:25","date_gmt":"2019-08-16T17:02:25","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2019\/08\/inducing-pluripotency-through-multiple-routes"},"modified":"2019-08-16T10:02:25","modified_gmt":"2019-08-16T17:02:25","slug":"inducing-pluripotency-through-multiple-routes","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2019\/08\/inducing-pluripotency-through-multiple-routes","title":{"rendered":"Inducing Pluripotency Through Multiple Routes"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/inducing-pluripotency-through-multiple-routes2.jpg\"><\/a><\/p>\n<p>A new <a href=\"https:\/\/www.cell.com\/cell-stem-cell\/fulltext\/S1934-5909%2819%2930307-8\" target=\"_blank\" rel=\"noopener\">study<\/a> outlines multiple ways in which epiblast stem cells can be reprogrammed back into a fully pluripotent state, paving the way for a better understanding of epigenetics.<\/p>\n<p><strong>The role of epigenetics<\/strong><\/p>\n<p>Epigenetics are why our cells, which all have the same DNA, differ in function. A bone cell has the same genetics as a nerve cell, but its epigenetic switches instruct it to perform the functions of a bone cell and not a nerve cell. <a href=\"https:\/\/www.leafscience.org\/aging-epigenetic-alterations\/\">Epigenetic alterations<\/a>, however, are one of the primary hallmarks of aging. As we age, harmful epigenetic switches are activated and beneficial ones are deactivated, causing age-related dysfunction. This may even lead to inflammation, which causes further epigenetic damage, leading to a dangerous feedback loop.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new study outlines multiple ways in which epiblast stem cells can be reprogrammed back into a fully pluripotent state, paving the way for a better understanding of epigenetics. The role of epigenetics Epigenetics are why our cells, which all have the same DNA, differ in function. A bone cell has the same genetics as [\u2026]<\/p>\n","protected":false},"author":370,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,269],"tags":[],"class_list":["post-94861","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/94861","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/370"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=94861"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/94861\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=94861"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=94861"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=94861"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}