{"id":94720,"date":"2019-08-13T05:03:20","date_gmt":"2019-08-13T12:03:20","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2019\/08\/ebola-is-now-curable-heres-how-the-new-treatments-work"},"modified":"2019-08-13T05:03:20","modified_gmt":"2019-08-13T12:03:20","slug":"ebola-is-now-curable-heres-how-the-new-treatments-work","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2019\/08\/ebola-is-now-curable-heres-how-the-new-treatments-work","title":{"rendered":"Ebola Is Now Curable. Here\u2019s How the New Treatments Work"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/ebola-is-now-curable-heres-how-the-new-treatments-work2.jpg\"><\/a><\/p>\n<p>Amid unrelenting <a href=\"https:\/\/www.wired.com\/story\/an-ebola-outbreak-in-a-war-zone-is-about-as-bad-as-it-gets\/\">chaos and violence<\/a>, scientists and doctors in the Democratic Republic of Congo have been running a clinical trial of new drugs to try to combat a <a href=\"https:\/\/www.wired.com\/story\/the-drc-ebola-outbreak-is-an-end-of-year-nightmare\/\">year-long Ebola outbreak<\/a>. On Monday, the trial\u2019s cosponsors at the World Health Organization and the National Institutes of Health announced that two of the experimental treatments appear to dramatically boost survival rates.<\/p>\n<p>While <a href=\"https:\/\/www.wired.com\/story\/an-ebola-vaccine-gets-its-first-real-world-test\/\">an experimental vaccine<\/a> previously had been shown to shield people from catching Ebola, the news marks a first for people who already have been infected. \u201cFrom now on, we will no longer say that Ebola is incurable,\u201d said Jean-Jacques Muyembe, director general of the Institut National de Recherche Biomedicale in the DRC, which has overseen the trial\u2019s operations on the ground.<\/p>\n<p>Starting last November, patients in four treatment centers in the country\u2019s east, where the outbreak is at its worst, were randomly assigned to receive one of four investigational therapies\u2014either an antiviral drug called remdesivir or one of three drugs that use monoclonal antibodies. Scientists concocted these big, Y-shaped proteins to recognize the specific shapes of invading bacteria and viruses and then recruit immune cells to attack those pathogens. One of these, a drug called ZMapp, is currently considered the standard of care during Ebola outbreaks. It had been tested and used during <a href=\"https:\/\/www.wired.com\/2015\/05\/one-year-later-ebolas-lessons-next-big-outbreak\/\">the devastating Ebola epidemic in West Africa<\/a> in 2014, and the goal was to see if those other drugs could outperform it. But preliminary data from the first 681 patients (out of a planned 725) showed such strong results that the trial has now been stopped.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Amid unrelenting chaos and violence, scientists and doctors in the Democratic Republic of Congo have been running a clinical trial of new drugs to try to combat a year-long Ebola outbreak. On Monday, the trial\u2019s cosponsors at the World Health Organization and the National Institutes of Health announced that two of the experimental treatments appear [\u2026]<\/p>\n","protected":false},"author":464,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1495],"tags":[],"class_list":["post-94720","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/94720","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/464"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=94720"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/94720\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=94720"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=94720"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=94720"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}