{"id":94248,"date":"2019-07-30T09:22:52","date_gmt":"2019-07-30T16:22:52","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2019\/07\/researchers-repair-faulty-brain-circuits-using-nanotechnology"},"modified":"2019-07-30T09:22:52","modified_gmt":"2019-07-30T16:22:52","slug":"researchers-repair-faulty-brain-circuits-using-nanotechnology","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2019\/07\/researchers-repair-faulty-brain-circuits-using-nanotechnology","title":{"rendered":"Researchers repair faulty brain circuits using nanotechnology"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/researchers-repair-faulty-brain-circuits-using-nanotechnology.jpg\"><\/a><\/p>\n<p>Working with mouse and human tissue, Johns Hopkins Medicine researchers report new evidence that a protein pumped out of some\u2014but not all\u2014populations of \u201chelper\u201d cells in the brain, called astrocytes, plays a specific role in directing the formation of connections among neurons needed for learning and forming new memories.<\/p>\n<p>Using mice genetically engineered and bred with fewer such connections, the researchers conducted proof-of-concept experiments that show they could deliver corrective proteins via nanoparticles to replace the missing protein needed for \u201croad repairs\u201d on the defective neural highway.<\/p>\n<p>Since such connective networks are lost or damaged by <a href=\"https:\/\/medicalxpress.com\/tags\/neurodegenerative+diseases\/\" rel=\"tag\" class=\"\">neurodegenerative diseases<\/a> such as Alzheimer\u2019s or certain types of intellectual disability, such as Norrie disease, the researchers say their findings advance efforts to regrow and repair the networks and potentially restore normal brain function.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Working with mouse and human tissue, Johns Hopkins Medicine researchers report new evidence that a protein pumped out of some\u2014but not all\u2014populations of \u201chelper\u201d cells in the brain, called astrocytes, plays a specific role in directing the formation of connections among neurons needed for learning and forming new memories. Using mice genetically engineered and bred [\u2026]<\/p>\n","protected":false},"author":511,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,4,47],"tags":[],"class_list":["post-94248","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-nanotechnology","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/94248","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/511"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=94248"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/94248\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=94248"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=94248"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=94248"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}