{"id":93140,"date":"2019-07-05T03:02:49","date_gmt":"2019-07-05T10:02:49","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2019\/07\/researchers-develop-promising-reconstruction-method-based-on-3d-printed-esophageal-grafts"},"modified":"2019-07-05T03:02:49","modified_gmt":"2019-07-05T10:02:49","slug":"researchers-develop-promising-reconstruction-method-based-on-3d-printed-esophageal-grafts","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2019\/07\/researchers-develop-promising-reconstruction-method-based-on-3d-printed-esophageal-grafts","title":{"rendered":"Researchers develop promising reconstruction method based on 3D-printed esophageal grafts"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/researchers-develop-promising-reconstruction-method-based-on-3d-printed-esophageal-grafts.jpg\"><\/a><\/p>\n<p>The loss of complete segments of the esophagus often results from treatments for esophageal cancer or congenital abnormalities, and current methods to re-establish continuity are inadequate. Now, working with a rat model, researchers have developed a promising reconstruction method based on the use of 3D-printed esophageal grafts. Their work is published in <em>Tissue Engineering,<\/em> a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.<\/p>\n<p>Eun-Jae Chung, MD, PhD, Seoul National University Hospital, Korea, Jung-Woog Shin, PhD, Inje University, Korea, and colleagues present their research in an article titled \u201cTissue-Engineered Esophagus via Bioreactor Cultivation for Circumferential Esophageal Reconstruction\u201d. The authors created a two-layered tubular scaffold with an electrospun nanofiber inner layer and 3D-printed strands in the outer layer. After seeding human mesenchymal stem cells on the inner layer, constructs were cultured in a bioreactor, and a new surgical technique was used for implantation, including the placement of a thyroid gland flap over the scaffold. <a href=\"https:\/\/www.news-medical.net\/health\/What-Does-Efficacy-Mean.aspx\" class=\"\">Efficacy<\/a> was compared with omentum-cultured scaffolding technology, and successful implantation and esophageal reconstruction were achieved based on several metrics.<\/p>\n<blockquote><p>Dr. Chung and colleagues from Korea present an exciting approach for esophageal repair using a combined 3D printing and bioreactor cultivation strategy. Critically, their work shows integration of the engineered esophageal tissue with host tissue, indicating a clinically viable strategy for circumferential esophageal reconstruction.\u201d<\/p><\/blockquote>\n","protected":false},"excerpt":{"rendered":"<p>The loss of complete segments of the esophagus often results from treatments for esophageal cancer or congenital abnormalities, and current methods to re-establish continuity are inadequate. Now, working with a rat model, researchers have developed a promising reconstruction method based on the use of 3D-printed esophageal grafts. Their work is published in Tissue Engineering, a [\u2026]<\/p>\n","protected":false},"author":444,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1489,11],"tags":[],"class_list":["post-93140","post","type-post","status-publish","format-standard","hentry","category-3d-printing","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/93140","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/444"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=93140"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/93140\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=93140"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=93140"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=93140"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}