{"id":93124,"date":"2019-07-04T13:02:26","date_gmt":"2019-07-04T20:02:26","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2019\/07\/cancer-cells-self-eating-tactic-may-be-its-weakness-2"},"modified":"2019-07-04T13:02:26","modified_gmt":"2019-07-04T20:02:26","slug":"cancer-cells-self-eating-tactic-may-be-its-weakness-2","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2019\/07\/cancer-cells-self-eating-tactic-may-be-its-weakness-2","title":{"rendered":"Cancer cell\u2019s \u201cself eating\u201d tactic may be its weakness"},"content":{"rendered":"<p><\/p>\n<p><iframe style=\"display: block; margin: 0 auto; width: 100%; aspect-ratio: 4\/3; object-fit: contain;\" src=\"https:\/\/www.youtube.com\/embed\/jZZ8lGZf7G0?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope;\n   picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<p><strong>Cold Spring Harbor, NY<\/strong> \u2014 Cancer cells use a bizarre strategy to reproduce in a tumor\u2019s low-energy environment; they mutilate their own mitochondria! Researchers at Cold Spring Harbor Laboratory (CSHL) also know how this occurs, offering a promising new target for pancreatic cancer therapies.<\/p>\n<p>Why would a cancer cell want to destroy its own functioning mitochondria? \u201cIt may seem pretty counterintuitive,\u201d admits M.D.-Ph. D. student Brinda Alagesan, a member of Dr. <a href=\"https:\/\/www.cshl.edu\/research\/faculty-staff\/david-tuveson\/\">David Tuveson\u2019s<\/a> lab at CSHL.<\/p>\n<p>According to Alagesan, the easiest way to think about why cancer cells may do this is to think of the mitochondria as a powerplant. \u201cThe mitochondria is the powerhouse of the cell,\u201d she recites, recalling the common grade school lesson. And just like a traditional powerplant, the mitochondria create their own pollution.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cold Spring Harbor, NY \u2014 Cancer cells use a bizarre strategy to reproduce in a tumor\u2019s low-energy environment; they mutilate their own mitochondria! Researchers at Cold Spring Harbor Laboratory (CSHL) also know how this occurs, offering a promising new target for pancreatic cancer therapies. Why would a cancer cell want to destroy its own functioning [\u2026]<\/p>\n","protected":false},"author":511,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,32,1506],"tags":[],"class_list":["post-93124","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-education","category-food"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/93124","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/511"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=93124"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/93124\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=93124"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=93124"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=93124"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}