{"id":91924,"date":"2019-06-11T09:02:27","date_gmt":"2019-06-11T16:02:27","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2019\/06\/nad-and-cellular-senescence-pathways-interact"},"modified":"2019-06-11T09:02:27","modified_gmt":"2019-06-11T16:02:27","slug":"nad-and-cellular-senescence-pathways-interact","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2019\/06\/nad-and-cellular-senescence-pathways-interact","title":{"rendered":"NAD+ and Cellular Senescence Pathways Interact"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/nad-and-cellular-senescence-pathways-interact.jpg\"><\/a><\/p>\n<p>A new publication highlights how the complex interaction of NAD+ and cellular senescence pathways may complicate proposed anti-aging therapies that boost NAD+ using precursors.<\/p>\n<p><strong>What are epigenetic alterations?<\/strong><\/p>\n<p>One of the <a href=\"https:\/\/www.leafscience.org\/aging-explained\/\">proposed reasons we age<\/a> is the changes to gene expression that our cells experience as we get older; these are commonly called <a href=\"https:\/\/www.leafscience.org\/aging-epigenetic-alterations\/\">epigenetic alterations<\/a>. These alterations harm the fundamental functions of our cells and can increase the risk of cancer and other age-related diseases.<\/p>\n<p><a href=\"https:\/\/www.leafscience.org\/nad-and-cellular-senescence-pathways-interact\/\" target=\"_blank\" rel=\"noopener noreferrer\"><\/p>\n<div style=\"clear:both;\">Read more<\/div>\n<p><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new publication highlights how the complex interaction of NAD+ and cellular senescence pathways may complicate proposed anti-aging therapies that boost NAD+ using precursors. What are epigenetic alterations? One of the proposed reasons we age is the changes to gene expression that our cells experience as we get older; these are commonly called epigenetic alterations. [\u2026]<\/p>\n","protected":false},"author":370,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,269],"tags":[],"class_list":["post-91924","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/91924","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/370"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=91924"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/91924\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=91924"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=91924"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=91924"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}