{"id":91503,"date":"2019-06-01T02:22:23","date_gmt":"2019-06-01T09:22:23","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2019\/06\/quick-liquid-packaging-encasing-water-silhouettes-in-3d-polymer-membranes-for-lab-in-a-drop-experiments"},"modified":"2019-06-01T02:22:23","modified_gmt":"2019-06-01T09:22:23","slug":"quick-liquid-packaging-encasing-water-silhouettes-in-3d-polymer-membranes-for-lab-in-a-drop-experiments","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2019\/06\/quick-liquid-packaging-encasing-water-silhouettes-in-3d-polymer-membranes-for-lab-in-a-drop-experiments","title":{"rendered":"Quick liquid packaging: Encasing water silhouettes in 3D polymer membranes for lab-in-a-drop experiments"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/quick-liquid-packaging-encasing-water-silhouettes-in-3d-polymer-membranes-for-lab-in-a-drop-experiments.gif\"><\/a><\/p>\n<p>The ability to confine water in an enclosed compartment without directly manipulating it or using rigid containers is an attractive possibility. In a recent study, Sara Coppola and an interdisciplinary research team in the departments of Biomaterials, Intelligent systems, Industrial Production Engineering and Advanced Biomaterials for Healthcare in Italy, proposed a water-based, <a href=\"https:\/\/www.nature.com\/collections\/bsmxgstsgy\">bottom-up<\/a> approach to encase facile, short-lived water silhouettes in a custom-made adaptive suit.<\/p>\n<p>In the work, they used a biocompatible <a href=\"https:\/\/phys.org\/tags\/polymer\/\" rel=\"tag\" class=\"\">polymer<\/a> that could self-assemble with unprecedented degrees of freedom on the <a href=\"https:\/\/phys.org\/tags\/water\/\" rel=\"tag\" class=\"\">water<\/a> surface to produce a <a href=\"https:\/\/phys.org\/tags\/thin+membrane\/\" rel=\"tag\" class=\"\">thin membrane<\/a>. They custom designed the polymer film as an external container of a liquid core or as a free-standing layer. The scientists characterized the physical properties and morphology of the <a href=\"https:\/\/phys.org\/tags\/membrane\/\" rel=\"tag\" class=\"\">membrane<\/a> and proposed a variety of applications for the phenomenon from the nanoscale to the macroscale. The process could encapsulate cells or microorganisms successfully without harm, opening the way to a breakthrough approach applicable for <a href=\"https:\/\/phys.org\/search\/?search=organ-on-a-chip&s=0\">organ-on-a-chip<\/a> and <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0165993606001397\">lab-in-a-drop<\/a> experiments. The results are now published in <i>Science<\/i> Advances.<\/p>\n<p>The possibility of isolating, engineering and shaping materials into 2-D or 3D objects from the nanometer to the microscale via bottom-up engineering is gaining importance in <a href=\"https:\/\/phys.org\/search\/?search=materials+science&s=0\">materials science<\/a>. Understanding the physics and chemistry of materials will allow a variety of applications in <a href=\"https:\/\/pubs.rsc.org\/en\/content\/articlelanding\/2013\/cp\/c2cp44593j\/unauth#!divAbstract\">microelectronics<\/a>, <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/10840199?dopt=Abstract\">drug delivery<\/a>, <a href=\"https:\/\/pubs.rsc.org\/en\/content\/articlelanding\/2014\/nr\/c4nr06500j\/unauth#!divAbstract\">forensics,<\/a> archeology and paleontology and space research. Materials scientists use a variety of technical methods for <a href=\"https:\/\/www.sciencedirect.com\/topics\/materials-science\/microfabrication\">microfabrication<\/a> including <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1369702117303917\">two-photon polymerization<\/a>, <a href=\"https:\/\/aip.scitation.org\/doi\/abs\/10.1063\/1.2764244?journalCode=jap\">soft interference lithography<\/a>, replica molding and <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2352431616301262\">self-folding polymers<\/a> to shape and isolate the material of interest. However, most materials engineering protocols require chemical and physical pretreatments to gain the desired final properties.<\/p>\n<p><a href=\"https:\/\/phys.org\/news\/2019-05-quick-liquid-packaging-encasing-silhouettes.html\" target=\"_blank\" rel=\"noopener noreferrer\"><\/p>\n<div style=\"clear:both;\">Read more<\/div>\n<p><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The ability to confine water in an enclosed compartment without directly manipulating it or using rigid containers is an attractive possibility. In a recent study, Sara Coppola and an interdisciplinary research team in the departments of Biomaterials, Intelligent systems, Industrial Production Engineering and Advanced Biomaterials for Healthcare in Italy, proposed a water-based, bottom-up approach to [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,19,38,4],"tags":[],"class_list":["post-91503","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-chemistry","category-engineering","category-nanotechnology"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/91503","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=91503"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/91503\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=91503"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=91503"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=91503"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}