{"id":90699,"date":"2019-05-14T12:22:46","date_gmt":"2019-05-14T19:22:46","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2019\/05\/bone-cells-suppress-cancer-metastases"},"modified":"2019-05-14T12:22:46","modified_gmt":"2019-05-14T19:22:46","slug":"bone-cells-suppress-cancer-metastases","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2019\/05\/bone-cells-suppress-cancer-metastases","title":{"rendered":"Bone cells suppress cancer metastases"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/bone-cells-suppress-cancer-metastases2.jpg\"><\/a><\/p>\n<p>In breast cancer, there are cases of women and men whose cancer returns in their bones 20\u201330 years after they were treated for their primary disease and thought they were cancer-free. This phenomenon always puzzled Jefferson researcher Karen Bussard, Ph.D. How is it possible that breast cancer cells from a primary tumor are able to reach the bones when a patient is deemed \u201ccancer-free\u201d after treatment? What was happening in bones that allowed the cancer cells to remain there for up to 30 years, alive but in a sleeping state, only to re-awaken decades later? In a step towards answering these questions, Dr. Bussard recently discovered a type of bone cell that can subdue cancer cells, slowing their growth, even in one of the most aggressive types of breast cancer: triple negative.<\/p>\n<p>The results, published in <i><i>Breast Cancer Research<\/i>,<\/i> raise intriguing questions about how these <a href=\"https:\/\/medicalxpress.com\/tags\/bone+cells\/\" rel=\"tag\" class=\"\">bone cells<\/a> exert their sleep-inducing influence, and whether it\u2019s possible to replicate and permanently turn cancers dormant.<\/p>\n<p>\u201cCancer has this uncanny ability to turn other cell types it comes in contact with to the <a href=\"https:\/\/medicalxpress.com\/tags\/cancer\/\" rel=\"tag\" class=\"\">cancer<\/a> cell\u2019s advantage,\u201d says Dr. Bussard, Assistant Professor of Cancer Biology at Thomas Jefferson University and a researcher at the Sidney Kimmel Cancer Center\u2014Jefferson Health. \u201cFor example, cancer cells can turn the immune cells that should kill it, into its own guards. However, we have now found a population of bone cells that not only resists, but subdues the cancer. It\u2019s fascinating.\u201d<\/p>\n<p><a href=\"https:\/\/medicalxpress.com\/news\/2019-05-bone-cells-suppress-cancer-metastases.html\" target=\"_blank\" rel=\"noopener noreferrer\"><\/p>\n<div style=\"clear:both;\">Read more<\/div>\n<p><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In breast cancer, there are cases of women and men whose cancer returns in their bones 20\u201330 years after they were treated for their primary disease and thought they were cancer-free. This phenomenon always puzzled Jefferson researcher Karen Bussard, Ph.D. How is it possible that breast cancer cells from a primary tumor are able to [\u2026]<\/p>\n","protected":false},"author":511,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1495],"tags":[],"class_list":["post-90699","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/90699","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/511"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=90699"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/90699\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=90699"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=90699"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=90699"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}