{"id":89115,"date":"2019-04-01T08:24:25","date_gmt":"2019-04-01T15:24:25","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2019\/04\/depression-obesity-chronic-pain-could-be-treated"},"modified":"2019-04-06T13:54:05","modified_gmt":"2019-04-06T20:54:05","slug":"depression-obesity-chronic-pain-could-be-treated","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2019\/04\/depression-obesity-chronic-pain-could-be-treated","title":{"rendered":"Depression, obesity, chronic pain could be treated by targeting the same key protein"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/depression-obesity-chronic-pain-could-be-treated2.jpg\"><\/a><\/p>\n<p>Major depression, obesity and chronic pain are all linked to the effects of one protein, called \u201cFK506-binding protein 51,\u201d or FKBP51. Until now, efforts to inhibit this target have been hampered by the difficulty of finding something specific enough to do the job and not affect similar proteins. Now a research group has developed a highly selective compound that can effectively block FKBP51 in mice, relieving chronic pain and having positive effects on diet-induced obesity and mood. The new compound also could have applications in alcoholism and brain cancer.<\/p>\n<p><a href=\"https:\/\/phys.org\/news\/2019-04-depression-obesity-chronic-pain-key.html\" target=\"_blank\" rel=\"noopener noreferrer\"><\/a><\/p>\n<div style=\"clear:both;\"><a href=\"https:\/\/phys.org\/news\/2019-04-depression-obesity-chronic-pain-key.html\" target=\"_blank\" rel=\"noopener noreferrer\">Read more<\/a><\/div>\n<p><a href=\"https:\/\/phys.org\/news\/2019-04-depression-obesity-chronic-pain-key.html\" target=\"_blank\" rel=\"noopener noreferrer\"><br \/>\n<\/a><a href=\"https:\/\/phys.org\/news\/2019-04-depression-obesity-chronic-pain-key.html\" target=\"_blank\" rel=\"noopener noreferrer\"><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Major depression, obesity and chronic pain are all linked to the effects of one protein, called \u201cFK506-binding protein 51,\u201d or FKBP51. Until now, efforts to inhibit this target have been hampered by the difficulty of finding something specific enough to do the job and not affect similar proteins. Now a research group has developed a [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-89115","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/89115","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=89115"}],"version-history":[{"count":2,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/89115\/revisions"}],"predecessor-version":[{"id":89285,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/89115\/revisions\/89285"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=89115"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=89115"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=89115"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}