{"id":88951,"date":"2019-03-26T16:02:25","date_gmt":"2019-03-26T23:02:25","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2019\/03\/gene-editing-record-smashed-with-over-13000-changes-made-to-a-single-human-cell"},"modified":"2019-03-26T16:02:25","modified_gmt":"2019-03-26T23:02:25","slug":"gene-editing-record-smashed-with-over-13000-changes-made-to-a-single-human-cell","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2019\/03\/gene-editing-record-smashed-with-over-13000-changes-made-to-a-single-human-cell","title":{"rendered":"Gene-Editing Record Smashed With Over 13,000 Changes Made to a Single Human Cell"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/gene-editing-record-smashed-with-over-13000-changes-made-to-a-single-human-cell2.jpg\"><\/a><\/p>\n<p>Using a modified version of CRISPR, a team of geneticists has successfully triggered 13,200 genetic changes to a single human cell. That\u2019s a new record, by a long shot. This sweeping new editing process could eventually be used to strip DNA of useless or dangerous genetic information\u2014or create entirely new kinds of life.<\/p>\n<p>New <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/574020v1\" target=\"_blank\" rel=\"noopener\">research<\/a> uploaded to the preprint bioRxiv server describes the achievement, in which a Harvard University team led by George Church edited the living crap out of a single human cell to the tune of 13,200 total modifications. Incredibly, the cell survived. The previous record for bulk edits made to a single cell was set in 2017, when Church and his colleagues knocked out <a href=\"http:\/\/science.sciencemag.org\/content\/357\/6357\/1303?utm_source=SciPak%20%28updated%206\/30\/2017%29&utm_campaign=ab5411c630-EMAIL_CAMPAIGN_2017_08_04&utm_medium=email&utm_term=0_10c5e799a3-ab5411c630-126514817\" target=\"_blank\" rel=\"noopener\">62 copies of a retrovirus<\/a> found in pig genomes. The new achievement is thus \u201cthree orders of magnitude greater\u201d than the previous standard, the authors wrote in their paper.<\/p>\n<p><!-- Link: <a href=\"https:\/\/gizmodo.com\/gene-editing-record-smashed-with-over-13-000-changes-ma-1833582283\">https:\/\/gizmodo.com\/gene-editing-record-smashed-with-over-13...1833582283<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Using a modified version of CRISPR, a team of geneticists has successfully triggered 13,200 genetic changes to a single human cell. That\u2019s a new record, by a long shot. This sweeping new editing process could eventually be used to strip DNA of useless or dangerous genetic information\u2014or create entirely new kinds of life. New research [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-88951","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/88951","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=88951"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/88951\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=88951"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=88951"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=88951"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}