{"id":88112,"date":"2019-02-23T09:02:23","date_gmt":"2019-02-23T17:02:23","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2019\/02\/new-interspecies-communication-strategy-between-gut-bacteria-and-mammalian-hosts-uncovered"},"modified":"2019-02-23T09:02:23","modified_gmt":"2019-02-23T17:02:23","slug":"new-interspecies-communication-strategy-between-gut-bacteria-and-mammalian-hosts-uncovered","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2019\/02\/new-interspecies-communication-strategy-between-gut-bacteria-and-mammalian-hosts-uncovered","title":{"rendered":"New \u2018interspecies communication\u2019 strategy between gut bacteria and mammalian hosts uncovered"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/new-interspecies-communication-strategy-between-gut-bacteria-and-mammalian-hosts-uncovered.jpg\"><\/a><\/p>\n<p>A study published today in <em>Cell<\/em> describes a form of \u201cinterspecies communication\u201d in which bacteria secrete a specific molecule \u2014 nitric oxide \u2014 that allows them to communicate with and control their hosts\u2019 DNA, and suggests that the conversation between the two may broadly influence human health.<\/p>\n<p>The researchers out of Case Western Reserve University School of Medicine, University Hospitals Cleveland Medical Center, and Harvard Medical School tracked nitric oxide secreted by gut bacteria inside tiny worms (<em>C. elegans<\/em>, a common mammalian laboratory model). Nitric oxide secreted by gut bacteria attached to thousands of host proteins, completely changing a worm\u2019s ability to regulate its own gene expression.<\/p>\n<p>The study is the first to show gut bacteria can tap into nitric oxide networks ubiquitous in mammals, including humans. Nitric oxide attaches to human proteins in a carefully regulated manner \u2014 a process known as S-nitrosylation \u2014 and disruptions are broadly implicated in diseases such as Alzheimer\u2019s, Parkinson\u2019s, asthma, diabetes, heart disease, and cancer.<\/p>\n<p><!-- Link: <a href=\"https:\/\/www.sciencedaily.com\/releases\/2019\/02\/190221130252.htm\">https:\/\/www.sciencedaily.com\/releases\/2019\/02\/190221130252.htm<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A study published today in Cell describes a form of \u201cinterspecies communication\u201d in which bacteria secrete a specific molecule \u2014 nitric oxide \u2014 that allows them to communicate with and control their hosts\u2019 DNA, and suggests that the conversation between the two may broadly influence human health. The researchers out of Case Western Reserve University [\u2026]<\/p>\n","protected":false},"author":501,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1495,47],"tags":[],"class_list":["post-88112","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-health","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/88112","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/501"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=88112"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/88112\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=88112"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=88112"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=88112"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}