{"id":88016,"date":"2019-02-20T10:02:23","date_gmt":"2019-02-20T18:02:23","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2019\/02\/a-crispr-gene-therapy-for-hutchinson-gilford-progeria"},"modified":"2019-02-20T10:02:23","modified_gmt":"2019-02-20T18:02:23","slug":"a-crispr-gene-therapy-for-hutchinson-gilford-progeria","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2019\/02\/a-crispr-gene-therapy-for-hutchinson-gilford-progeria","title":{"rendered":"A CRISPR Gene Therapy for Hutchinson-Gilford Progeria"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/a-crispr-gene-therapy-for-hutchinson-gilford-progeria.jpg\"><\/a><\/p>\n<p>Researchers at the Salk Institute have moved a step closer to a possible therapy for Hutchinson-Gilford progeria syndrome, a rare genetic disorder that is often described as accelerated aging, as people with it appear to age far faster than normal. Using a new CRISPR\/Cas9 gene therapy in a mouse model, they were able to slow down the pace of the condition, improve health, and increase lifespan.<\/p>\n<p><strong>What is Hutchinson-Gilford progeria?<\/strong><\/p>\n<p>Progeria is a degenerative disorder caused by a mutation in the LMNA gene. This disease has an early onset and progresses rapidly, and animals and humans with progeria show symptoms that are similar to regular aging, only on a much-accelerated timescale, giving them drastically shorter lifespans than normal. Humans with this condition rarely live very long, with the average being only 13 years old.<\/p>\n<p><!-- Link: <a href=\"https:\/\/www.leafscience.org\/a-crispr-gene-therapy-for-hutchinson-gilford-progeria\/\">https:\/\/www.leafscience.org\/a-crispr-gene-therapy-for-hutchi...-progeria\/<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers at the Salk Institute have moved a step closer to a possible therapy for Hutchinson-Gilford progeria syndrome, a rare genetic disorder that is often described as accelerated aging, as people with it appear to age far faster than normal. Using a new CRISPR\/Cas9 gene therapy in a mouse model, they were able to slow [\u2026]<\/p>\n","protected":false},"author":370,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,269],"tags":[],"class_list":["post-88016","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/88016","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/370"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=88016"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/88016\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=88016"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=88016"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=88016"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}