{"id":85377,"date":"2018-12-02T08:02:27","date_gmt":"2018-12-02T16:02:27","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2018\/12\/precision-genome-engineering"},"modified":"2018-12-02T08:02:27","modified_gmt":"2018-12-02T16:02:27","slug":"precision-genome-engineering","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2018\/12\/precision-genome-engineering","title":{"rendered":"Precision genome engineering"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/precision-genome-engineering.jpg\"><\/a><\/p>\n<p>Biotechnology<br \/> Genome editing through CRISPR-Cas systems has the potential to correct genetic mutations that occur in diseased cells, such as cancer cells. However, the ability to selectively activate CRISPR-Cas systems in diseased cells is important to ensure that gene editing only occurs where it is wanted. Zhu et al. developed a system whereby gene editing could be activated by a magnetic field, thus allowing spatial control. The use of nanomagnets in their system also improved transduction into target cells in tumor-bearing mouse models. This approach could potentially allow the translation of CRISPR-Cas systems into therapeutic agents.<\/p>\n<p>Nat. Biomed. Eng. 10.1038\/s41551-018\u20110318-7 (2018).<\/p>\n<p><!-- Link: <a href=\"http:\/\/science.sciencemag.org\/content\/362\/6418\/1015.2.full\">http:\/\/science.sciencemag.org\/content\/362\/6418\/1015.2.full<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Biotechnology Genome editing through CRISPR-Cas systems has the potential to correct genetic mutations that occur in diseased cells, such as cancer cells. However, the ability to selectively activate CRISPR-Cas systems in diseased cells is important to ensure that gene editing only occurs where it is wanted. Zhu et al. developed a system whereby gene editing [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,412],"tags":[],"class_list":["post-85377","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/85377","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=85377"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/85377\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=85377"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=85377"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=85377"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}