{"id":83800,"date":"2018-10-18T21:43:04","date_gmt":"2018-10-19T04:43:04","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2018\/10\/crispr-heals-genetic-liver-disorder-in-mice"},"modified":"2018-10-18T21:43:04","modified_gmt":"2018-10-19T04:43:04","slug":"crispr-heals-genetic-liver-disorder-in-mice","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2018\/10\/crispr-heals-genetic-liver-disorder-in-mice","title":{"rendered":"CRISPR heals genetic liver disorder in mice"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/crispr-heals-genetic-liver-disorder-in-mice2.jpg\"><\/a><\/p>\n<p>Researchers healed mice with a genetic metabolic disorder that also affects humans by using a new editing tool to target and correct genetic mutations.<\/p>\n<p>Some babies are born with the metabolic disorder phenylketonuria and need a special diet so that the amino acid phenylalanine doesn\u2019t accumulate in the body. Excess phenylalanine delays mental and motor development. If left untreated, the children may develop mental disabilities.<\/p>\n<p>The cause of this metabolic disorder is a mutation in a gene that provides the blueprint for the enzyme phenylalanine hydroxylase (Pah). The enzyme, which is produced by the cells of the liver, metabolizes phenylalanine.<\/p>\n<p><!-- Link: <a href=\"https:\/\/www.futurity.org\/crispr-gene-editing-1891632\/\">https:\/\/www.futurity.org\/crispr-gene-editing-1891632\/<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers healed mice with a genetic metabolic disorder that also affects humans by using a new editing tool to target and correct genetic mutations. Some babies are born with the metabolic disorder phenylketonuria and need a special diet so that the amino acid phenylalanine doesn\u2019t accumulate in the body. Excess phenylalanine delays mental and motor [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,47],"tags":[],"class_list":["post-83800","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/83800","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=83800"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/83800\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=83800"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=83800"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=83800"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}