{"id":83526,"date":"2018-10-11T10:03:00","date_gmt":"2018-10-11T17:03:00","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2018\/10\/the-first-therapy-that-targets-aging-is-in-human-trials-now"},"modified":"2018-10-11T10:03:00","modified_gmt":"2018-10-11T17:03:00","slug":"the-first-therapy-that-targets-aging-is-in-human-trials-now","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2018\/10\/the-first-therapy-that-targets-aging-is-in-human-trials-now","title":{"rendered":"The First Therapy that Targets Aging is in Human Trials Now"},"content":{"rendered":"<p><\/p>\n<p><iframe style=\"display: block; margin: 0 auto; width: 100%; aspect-ratio: 4\/3; object-fit: contain;\" src=\"https:\/\/www.youtube.com\/embed\/6A1knkZiysQ?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope;\n   picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<p>Senolytics are the first therapies that directly target the aging process to delay or prevent age-related diseases and are now in human trials. Today we thought it was the ideal time to have a look at how they work and the companies involved.<\/p>\n<p><strong>Senescent cells and aging<\/strong><\/p>\n<p>As we get older, more and more of our the cells in our bodies become dysfunctional and enter into a state known as senescence. These senescent cells no longer divide or support the tissues and organs of which they are part; instead, they secrete a range of harmful inflammatory chemical signals, which are known as the senescence-associated secretory phenotype (SASP).<\/p>\n<p><!-- Link: <a href=\"https:\/\/www.leafscience.org\/senolytics-target-aging\/\">https:\/\/www.leafscience.org\/senolytics-target-aging\/<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Senolytics are the first therapies that directly target the aging process to delay or prevent age-related diseases and are now in human trials. Today we thought it was the ideal time to have a look at how they work and the companies involved. Senescent cells and aging As we get older, more and more of [\u2026]<\/p>\n","protected":false},"author":370,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269],"tags":[],"class_list":["post-83526","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/83526","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/370"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=83526"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/83526\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=83526"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=83526"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=83526"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}