{"id":83338,"date":"2018-10-06T17:02:13","date_gmt":"2018-10-07T00:02:13","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2018\/10\/can-supplementation-with-nmn-increase-longevity"},"modified":"2018-10-07T17:00:55","modified_gmt":"2018-10-08T00:00:55","slug":"can-supplementation-with-nmn-increase-longevity","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2018\/10\/can-supplementation-with-nmn-increase-longevity","title":{"rendered":"Can supplementation with NMN Increase Longevity?"},"content":{"rendered":"<p><\/p>\n<p><iframe style=\"display: block; margin: 0 auto; width: 100%; aspect-ratio: 4\/3; object-fit: contain;\" src=\"https:\/\/www.youtube.com\/embed\/OwLog8_C4lE?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope;\n   picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<blockquote><p>Recently, we have shown that <strong>by administering the <a href=\"https:\/\/www.lifespan.io\/wp-content\/uploads\/2016\/05\/DavidSinclair_NMNCampaign_Synthetic_Pathway.jpg\" target=\"_blank\" rel=\"noopener\">NAD+ precursor NMN (Nicotinamide Mononucleotide)<\/a><\/strong>in normal drinking water to older mice, <strong>NAD+ levels were restored<\/strong> to those normally associated with younger healthy animals. By administering NMN to mice for just one week, <strong>our lab demonstrated a robust correction in age-associated metabolic dysfunction<\/strong><strong> and restored muscle mitochondrial function in old mice to levels seen in younger control mice <\/strong>(<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4076149\/\" target=\"_blank\" rel=\"noopener\">Gomes et al. 2013<\/a>)<strong>.<\/strong><\/p>\n<\/blockquote>\n<p><a href=\"https:\/\/www.lifespan.io\/campaigns\/can-nmn-increase-longevity\/?mc_cid=9f24c0f697&mc_eid=019dfcda6c\" rel=\"nofollow\"><a href=\"https:\/\/www.lifespan.io\/campaigns\/can-nmn-increase-longevity\/?mc_cid=9f24c0f697&mc_eid=019dfcda6c\">https:\/\/www.lifespan.io\/campaigns\/can-nmn-increase-longevity\u2026019dfcda6c<\/a><\/a><\/p>\n<p><!-- Link: <a href=\"https:\/\/scienceofsingularity.com\/2018\/10\/06\/can-supplementation-with-nmn-increase-longevity\/\">https:\/\/scienceofsingularity.com\/2018\/10\/06\/can-supplementat...longevity\/<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Recently, we have shown that by administering the NAD+ precursor NMN (Nicotinamide Mononucleotide)in normal drinking water to older mice, NAD+ levels were restored to those normally associated with younger healthy animals. By administering NMN to mice for just one week, our lab demonstrated a robust correction in age-associated metabolic dysfunction and restored muscle mitochondrial function [\u2026]<\/p>\n","protected":false},"author":374,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269,17],"tags":[],"class_list":["post-83338","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension","category-sustainability"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/83338","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/374"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=83338"}],"version-history":[{"count":1,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/83338\/revisions"}],"predecessor-version":[{"id":83387,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/83338\/revisions\/83387"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=83338"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=83338"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=83338"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}