{"id":83074,"date":"2018-09-26T03:22:56","date_gmt":"2018-09-26T10:22:56","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2018\/09\/genetic-testing-not-a-one-and-done-deal"},"modified":"2018-09-26T03:22:56","modified_gmt":"2018-09-26T10:22:56","slug":"genetic-testing-not-a-one-and-done-deal","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2018\/09\/genetic-testing-not-a-one-and-done-deal","title":{"rendered":"Genetic testing: Not a one-and-done deal"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/genetic-testing-not-a-one-and-done-deal.jpg\"><\/a><\/p>\n<p>That conclusion is based on a study that reviewed genetic testing results from 1.45 million individuals and found that nearly 25 percent of \u201cvariants of uncertain significance\u201d were subsequently reclassified \u2014 sometimes as less likely to be associated with cancer, sometimes as more likely.<\/p>\n<p>The study appears in the <em>Journal of the American Medical Association <\/em>(<em>JAMA<\/em>).<\/p>\n<p>When variations from the norm are discovered in a gene, the variants are classified as \u201cbenign,\u201d \u201clikely benign,\u201d \u201cvariant of uncertain significance,\u201d \u201clikely pathogenic,\u201d or \u201cpathogenic.\u201d<\/p>\n<p><!-- Link: <a href=\"https:\/\/www.sciencedaily.com\/releases\/2018\/09\/180925140415.htm\">https:\/\/www.sciencedaily.com\/releases\/2018\/09\/180925140415.htm<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>That conclusion is based on a study that reviewed genetic testing results from 1.45 million individuals and found that nearly 25 percent of \u201cvariants of uncertain significance\u201d were subsequently reclassified \u2014 sometimes as less likely to be associated with cancer, sometimes as more likely. The study appears in the Journal of the American Medical Association [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-83074","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/83074","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=83074"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/83074\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=83074"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=83074"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=83074"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}