{"id":82468,"date":"2018-09-10T08:42:23","date_gmt":"2018-09-10T15:42:23","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2018\/09\/nmn-and-the-cell-membrane"},"modified":"2018-09-10T08:42:23","modified_gmt":"2018-09-10T15:42:23","slug":"nmn-and-the-cell-membrane","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2018\/09\/nmn-and-the-cell-membrane","title":{"rendered":"NMN and the Cell Membrane"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/nmn-and-the-cell-membrane.jpg\"><\/a><\/p>\n<p>Today, we are going to take a look at the topic of NAD+, its precursor, nicotinamide mononucleotide, and the debate surrounding the ability of these molecules to pass through the cell membrane.<\/p>\n<p><strong>NAD+ is critical for cellular function<\/strong><\/p>\n<p>Nicotinamide adenine dinucleotide (NAD+) is a redox cofactor, but it is also a critical signaling molecule that regulates cell function and survival in response to environmental changes such as nutrient intake and cellular damage. Age-related changes to the level of NAD+ in the cell impacts mitochondrial function, nutrient sensing and metabolism, redox reactions, circadian rhythm, immune and inflammatory responses, DNA repair, cell division, protein-to-protein signaling, chromatin, and epigenetics.<\/p>\n<p><!-- Link: <a href=\"https:\/\/www.leafscience.org\/nmn-crosses-cell-membrane\/\">https:\/\/www.leafscience.org\/nmn-crosses-cell-membrane\/<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Today, we are going to take a look at the topic of NAD+, its precursor, nicotinamide mononucleotide, and the debate surrounding the ability of these molecules to pass through the cell membrane. NAD+ is critical for cellular function Nicotinamide adenine dinucleotide (NAD+) is a redox cofactor, but it is also a critical signaling molecule that [\u2026]<\/p>\n","protected":false},"author":370,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,269],"tags":[],"class_list":["post-82468","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/82468","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/370"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=82468"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/82468\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=82468"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=82468"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=82468"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}