{"id":82391,"date":"2018-09-06T14:12:39","date_gmt":"2018-09-06T21:12:39","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2018\/09\/a-brain-boost-to-fight-alzheimers-disease"},"modified":"2018-09-06T14:12:39","modified_gmt":"2018-09-06T21:12:39","slug":"a-brain-boost-to-fight-alzheimers-disease","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2018\/09\/a-brain-boost-to-fight-alzheimers-disease","title":{"rendered":"A brain boost to fight Alzheimer\u2019s disease"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/a-brain-boost-to-fight-alzheimers-disease.jpg\"><\/a><\/p>\n<p>Alzheimer\u2019s disease is one of the biggest medical challenges of our time. About 30 million people worldwide are living with Alzheimer\u2019s disease, and the numbers are predicted to increase to 100 million by 2050 if we do not find effective prevention or treatment strategies (<em>1<\/em>). Substantial evidence suggests that leading a healthy lifestyle, including regular exercise, may lower the risk of developing Alzheimer\u2019s disease. However, the mechanisms through which exercise protects the brain and whether we could bottle these as a treatment remain controversial. On page 991 of this issue, Choi <em>et al.<\/em> (<em>2<\/em>) reveal that in a mouse model of Alzheimer\u2019s disease, exercise improves memory through a combination of encouraging neurogenesis in the hippocampus and increasing the levels of brain-derived neurotrophic factor (BDNF), a growth factor that supports neuronal survival. Their findings suggest that agents that promote both BDNF signaling and neurogenesis might be effective in preventing or treating Alzheimer\u2019s disease.<\/p>\n<p><a href=\"http:\/\/www.sciencemag.org\/about\/science-licenses-journal-article-reuse\" rel=\"license\"><a href=\"http:\/\/www.sciencemag.org\/about\/science-licenses-journal-article-reuse\">http:\/\/www.sciencemag.org\/about\/science-licenses-journal-article-reuse<\/a><\/a><\/p>\n<p>This is an article distributed under the terms of the <a href=\"http:\/\/www.sciencemag.org\/about\/science-licenses-journal-article-reuse\" rel=\"license\">Science Journals Default License<\/a>.<\/p>\n<p><!-- Link: <a href=\"http:\/\/science.sciencemag.org\/content\/361\/6406\/975\">http:\/\/science.sciencemag.org\/content\/361\/6406\/975<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Alzheimer\u2019s disease is one of the biggest medical challenges of our time. About 30 million people worldwide are living with Alzheimer\u2019s disease, and the numbers are predicted to increase to 100 million by 2050 if we do not find effective prevention or treatment strategies (1). Substantial evidence suggests that leading a healthy lifestyle, including regular [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1495,47],"tags":[],"class_list":["post-82391","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-health","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/82391","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=82391"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/82391\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=82391"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=82391"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=82391"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}