{"id":82384,"date":"2018-09-06T11:42:21","date_gmt":"2018-09-06T18:42:21","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2018\/09\/a-review-of-cellular-senescence-and-senolytics"},"modified":"2018-09-06T11:42:21","modified_gmt":"2018-09-06T18:42:21","slug":"a-review-of-cellular-senescence-and-senolytics","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2018\/09\/a-review-of-cellular-senescence-and-senolytics","title":{"rendered":"A Review of Cellular Senescence and Senolytics"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/a-review-of-cellular-senescence-and-senolytics.jpg\"><\/a><\/p>\n<p>Today, we want to point out a <a href=\"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S147149141830162X\">new publication<\/a> that dives into the world of senolytics, which are drugs or therapies that seek and destroy harmful non-dividing cells that resist the programmed cell death known as apoptosis.<\/p>\n<p>These cells linger in the body, and, as we age, more and more of them accumulate and contribute to the chronic age-related inflammation known as \u201cinflammaging\u201d while reducing tissue regeneration and repair and contributing to the development of various age-related diseases.<\/p>\n<p>One approach to dealing with these problem cells is to tip them over the edge and cause them to self-destruct, thus removing them and the inflammation they cause. A new class of drugs known as senolytics was discovered a few years ago, and the interest in developing them to potentially combat age-related diseases has been growing rapidly.<\/p>\n<p><!-- Link: <a href=\"https:\/\/www.leafscience.org\/a-review-of-cellular-senescence-and-senolytics\/\">https:\/\/www.leafscience.org\/a-review-of-cellular-senescence-and-senolytics\/<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Today, we want to point out a new publication that dives into the world of senolytics, which are drugs or therapies that seek and destroy harmful non-dividing cells that resist the programmed cell death known as apoptosis. These cells linger in the body, and, as we age, more and more of them accumulate and contribute [\u2026]<\/p>\n","protected":false},"author":370,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269],"tags":[],"class_list":["post-82384","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/82384","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/370"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=82384"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/82384\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=82384"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=82384"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=82384"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}