{"id":81979,"date":"2018-08-22T19:42:40","date_gmt":"2018-08-23T02:42:40","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2018\/08\/with-embryo-base-editing-china-gets-another-crispr-first"},"modified":"2018-08-22T19:42:40","modified_gmt":"2018-08-23T02:42:40","slug":"with-embryo-base-editing-china-gets-another-crispr-first","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2018\/08\/with-embryo-base-editing-china-gets-another-crispr-first","title":{"rendered":"With Embryo Base Editing, China Gets Another Crispr First"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/with-embryo-base-editing-china-gets-another-crispr-first.jpg\"><\/a><\/p>\n<p>Scientists in the US may be out in front developing the <a href=\"https:\/\/www.wired.com\/story\/whats-next-for-crispr\/\">next generation<\/a> of Crispr-based genetic tools, but it\u2019s China that\u2019s pushing those techniques toward human therapies the fastest. Chinese researchers were the first to <a href=\"https:\/\/www.nature.com\/news\/first-monkeys-with-customized-mutations-born-1.14611\" target=\"_blank\">Crispr monkeys<\/a>, and <a href=\"https:\/\/www.wired.com\/2015\/05\/read-freak-gene-edited-superbabies\/\">non-viable embryos<\/a>, and to stick Crispr\u2019d cells into <a href=\"https:\/\/www.wired.com\/2016\/11\/china-used-crispr-fight-cancer-real-live-human\/\">a real live human<\/a>. And now, a team of scientists in China have used a cutting-edge Crispr technique, known as <a href=\"https:\/\/www.wired.com\/story\/new-science-could-sharpen-crisprs-gene-editing-scalpel\/\">base editing<\/a>, to repair a disease-causing mutation in viable human embryos.<\/p>\n<p>Published last week in the <a href=\"https:\/\/www.cell.com\/molecular-therapy-family\/molecular-therapy\/fulltext\/S1525-0016%2818%2930378-2#%20\" target=\"_blank\">journal <em>Molecular Therapy<\/em><\/a>, and reported first <a href=\"https:\/\/www.statnews.com\/2018\/08\/20\/crispr-corrects-marfan-mutation-in-human-embryos\/\" target=\"_blank\">by <em>Stat<\/em><\/a>, the study represents significant progress over previous attempts to remodel the DNA of human embryos. That\u2019s in part because the editing worked so well, and in part because that editing took place in embryos created by a standard in-vitro fertilization technique.<\/p>\n<p>You\u2019ve read your last complimentary article this month. To read the full article, <a to=\"https:\/\/subscribe.condenastdigital.com\/subscribe\/splits\/wired\/WIR_Edit_Hardcoded?source=finalbarrier_text_failsafe\" href=\"https:\/\/subscribe.condenastdigital.com\/subscribe\/splits\/wired\/WIR_Edit_Hardcoded?source=finalbarrier_text_failsafe\">SUBSCRIBE NOW<\/a>. If you\u2019re already a subscriber, please <a href=\"https:\/\/www.wired.com\/account\/sign-in\/\">sign in<\/a> and and verify your subscription.<\/p>\n<p><!-- Link: <a href=\"https:\/\/www.wired.com\/story\/crispr-base-editing-first-china\/\">https:\/\/www.wired.com\/story\/crispr-base-editing-first-china\/<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scientists in the US may be out in front developing the next generation of Crispr-based genetic tools, but it\u2019s China that\u2019s pushing those techniques toward human therapies the fastest. Chinese researchers were the first to Crispr monkeys, and non-viable embryos, and to stick Crispr\u2019d cells into a real live human. And now, a team of [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-81979","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/81979","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=81979"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/81979\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=81979"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=81979"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=81979"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}