{"id":81433,"date":"2018-08-07T06:22:28","date_gmt":"2018-08-07T13:22:28","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2018\/08\/compounds-ap39-ap123-rt01-may-reverse-ageing-in-human-cell-study"},"modified":"2018-08-10T07:08:55","modified_gmt":"2018-08-10T14:08:55","slug":"compounds-ap39-ap123-rt01-may-reverse-ageing-in-human-cell-study","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2018\/08\/compounds-ap39-ap123-rt01-may-reverse-ageing-in-human-cell-study","title":{"rendered":"Compounds AP39, AP123, RT01 may reverse ageing in human cell: Study"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/compounds-ap39-ap123-rt01-may-reverse-ageing-in-human-cell-study.jpg\"><\/a><\/p>\n<p>The compounds \u2014 AP39, AP123 and RT01 \u2014 have been designed to selectively deliver minute quantities of the gas hydrogen sulphide to the mitochondria in cells and help the old or damaged cells to generate the \u2018energy\u2019 needed for survival and to reduce senescence.<\/p>\n<p>In the samples used, the number of senescent cells \u2014 older cells that have deteriorated and stopped dividing \u2014 was reduced by up to 50 per cent.<\/p>\n<p>The team also identified two splicing factors \u2014 a component of cells \u2014 that play a key role in when and how endothelial cells become senescent.<\/p>\n<p><!-- Link: <a href=\"http:\/\/www.newsnation.in\/science-news\/new-compound-may-reverse-human-cell-ageing-study-article-200162.html\">http:\/\/www.newsnation.in\/science-news\/new-compound-may-rever...00162.html<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The compounds \u2014 AP39, AP123 and RT01 \u2014 have been designed to selectively deliver minute quantities of the gas hydrogen sulphide to the mitochondria in cells and help the old or damaged cells to generate the \u2018energy\u2019 needed for survival and to reduce senescence. In the samples used, the number of senescent cells \u2014 older [\u2026]<\/p>\n","protected":false},"author":476,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269],"tags":[],"class_list":["post-81433","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/81433","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/476"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=81433"}],"version-history":[{"count":1,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/81433\/revisions"}],"predecessor-version":[{"id":81562,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/81433\/revisions\/81562"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=81433"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=81433"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=81433"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}