{"id":81039,"date":"2018-07-30T08:22:21","date_gmt":"2018-07-30T15:22:21","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2018\/07\/an-interview-with-dr-joao-pedro-de-magalhaes"},"modified":"2018-07-31T12:10:52","modified_gmt":"2018-07-31T19:10:52","slug":"an-interview-with-dr-joao-pedro-de-magalhaes","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2018\/07\/an-interview-with-dr-joao-pedro-de-magalhaes","title":{"rendered":"An Interview With Dr. Jo\u00e3o Pedro de Magalh\u00e3es"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/an-interview-with-dr-joao-pedro-de-magalhaes2.jpg\"><\/a><\/p>\n<p>A new interview on LEAF with biogerontologist Dr. Jo\u00e3o Pedro de Magalh\u00e3es.<\/p>\n<hr>\n<p>Today, we have an interview with Dr. Jo\u00e3o Pedro de Magalh\u00e3es, the biogerontologist who created and runs <a href=\"http:\/\/senescence.info\/\">senescence.info<\/a>. In the unlikely event that his name is new to you, we had another interview with him last year, which you can check out <a href=\"https:\/\/www.leafscience.org\/dr-joao-pedro-de-magalhaes-a-life-dedicated-to-conquering-ageing\/\">here<\/a>.<\/p>\n<p><strong>How do you think we age; are we programmed to die, do we wear out, or is the truth a mixture of both?<\/strong><\/p>\n<p>I don\u2019t think we wear out. Humans and complex animals are made of cells and molecules that, by and large, have some turnover; we can replace most of our components, so I don\u2019t think it\u2019s correct to see aging as wearing out, at least not in complex animals like humans. (Please see <a href=\"http:\/\/www.senescence.info\/genetics_of_aging.html#Aging_Is_Not_Wear_and_Tear\">here<\/a>.) That said, I do think that some forms of cumulative damage contribute to the aging process, such as DNA damage. I also think that there are programmatic aspects to aging. That is, I think that genetic programs coordinating some aspects of growth and development persist into adulthood and become detrimental as forms of antagonistic pleiotropy. It is probably a combination of molecular damage and the inadvertent actions of genetic programs that causes aging.<\/p>\n<p><!-- Link: <a href=\"https:\/\/www.leafscience.org\/an-interview-with-dr-joao-pedro-de-magalhaes\/\">https:\/\/www.leafscience.org\/an-interview-with-dr-joao-pedro-de-magalhaes\/<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new interview on LEAF with biogerontologist Dr. Jo\u00e3o Pedro de Magalh\u00e3es. Today, we have an interview with Dr. Jo\u00e3o Pedro de Magalh\u00e3es, the biogerontologist who created and runs senescence.info. In the unlikely event that his name is new to you, we had another interview with him last year, which you can check out here. [\u2026]<\/p>\n","protected":false},"author":418,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,269],"tags":[],"class_list":["post-81039","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/81039","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/418"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=81039"}],"version-history":[{"count":1,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/81039\/revisions"}],"predecessor-version":[{"id":81130,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/81039\/revisions\/81130"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=81039"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=81039"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=81039"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}