{"id":80318,"date":"2018-07-02T09:02:22","date_gmt":"2018-07-02T16:02:22","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2018\/07\/metformin-reverses-established-lung-fibrosis"},"modified":"2018-07-02T09:02:22","modified_gmt":"2018-07-02T16:02:22","slug":"metformin-reverses-established-lung-fibrosis","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2018\/07\/metformin-reverses-established-lung-fibrosis","title":{"rendered":"Metformin reverses established lung fibrosis"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/metformin-reverses-established-lung-fibrosis.jpg\"><\/a><\/p>\n<p>Researchers at the University of Alabama at Birmingham have shown\u2014for the first time\u2014that established lung fibrosis can be reversed using a drug treatment that targets cell metabolism.<\/p>\n<p>This novel finding, reported in the journal <i>Nature Medicine<\/i>, is important because, despite significant advances to reveal the pathological mechanisms of persistent <a href=\"https:\/\/medicalxpress.com\/tags\/fibrosis\/\" rel=\"tag\" class=\"\">fibrosis<\/a>, effective treatment interventions are lacking.<\/p>\n<p>Pulmonary fibrosis can develop after <a href=\"https:\/\/medicalxpress.com\/tags\/lung\/\" rel=\"tag\" class=\"\">lung<\/a> injuries like infections, radiation or chemotherapy, or it can have an unknown cause, as in <a href=\"https:\/\/medicalxpress.com\/tags\/idiopathic+pulmonary+fibrosis\/\" rel=\"tag\" class=\"\">idiopathic pulmonary fibrosis<\/a>, or IPF is a progressive, and ultimately fatal, <a href=\"https:\/\/medicalxpress.com\/tags\/lung+disorder\/\" rel=\"tag\" class=\"\">lung disorder<\/a> that strikes more than 150,000 patients a year in the United States and more than 5 million worldwide.<\/p>\n<p><!-- Link: <a href=\"https:\/\/medicalxpress.com\/news\/2018-07-metformin-reverses-lung-fibrosis.html\">https:\/\/medicalxpress.com\/news\/2018&#45;07-metformin-reverses-lung-fibrosis.html<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers at the University of Alabama at Birmingham have shown\u2014for the first time\u2014that established lung fibrosis can be reversed using a drug treatment that targets cell metabolism. This novel finding, reported in the journal Nature Medicine, is important because, despite significant advances to reveal the pathological mechanisms of persistent fibrosis, effective treatment interventions are lacking. [\u2026]<\/p>\n","protected":false},"author":461,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-80318","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/80318","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/461"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=80318"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/80318\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=80318"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=80318"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=80318"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}