{"id":77048,"date":"2018-03-20T21:02:44","date_gmt":"2018-03-21T04:02:44","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2018\/03\/targeting-levels-of-specific-protein-could-improve-memory-in-aging-reduce-symptoms-of-ptsd"},"modified":"2018-03-20T21:02:44","modified_gmt":"2018-03-21T04:02:44","slug":"targeting-levels-of-specific-protein-could-improve-memory-in-aging-reduce-symptoms-of-ptsd","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2018\/03\/targeting-levels-of-specific-protein-could-improve-memory-in-aging-reduce-symptoms-of-ptsd","title":{"rendered":"Targeting levels of specific protein could improve memory in aging, reduce symptoms of PTSD"},"content":{"rendered":"

<\/a><\/p>\n

A neural circuit mechanism involved in preserving the specificity of memories has been identified by investigators from the Massachusetts General Hospital (MGH) Center for Regenerative Medicine<\/a> and the Harvard Stem Cell Institute (HSCI)<\/a>.<\/p>\n

They also identified a genetic \u201cswitch\u201d that can slow down #memory<\/a> generalization \u2014 the loss of specific details over time that occurs in both age-related memory impairment and in post-traumatic stress disorder (#PTSD<\/a>), in which emotions originally produced by traumatic experiences are elicited in response to innocuous cues that have little resemblance to the traumatic memory.<\/p>\n

\u201cThe circuit mechanism we identified in mice allows us to preserve the precision or the details of memories over the passage of time in adult as well as aged animals,\u201d says Amar Sahay of the MGH Center for #Regenerative Medicine<\/a> and HSCI, corresponding author of a paper appearing in Nature Medicine. \u201cThese findings have implications for the generalization of traumatic memories in PTSD and for memory imprecision in #aging<\/a>.\u201d<\/p>\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

A neural circuit mechanism involved in preserving the specificity of memories has been identified by investigators from the Massachusetts General Hospital (MGH) Center for Regenerative Medicine and the Harvard Stem Cell Institute (HSCI). They also identified a genetic \u201cswitch\u201d that can slow down #memory generalization \u2014 the loss of specific details over time that occurs [\u2026]<\/p>\n","protected":false},"author":461,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,269,47],"tags":[],"class_list":["post-77048","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-life-extension","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/77048","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/461"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=77048"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/77048\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=77048"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=77048"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=77048"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}