{"id":76947,"date":"2018-03-16T09:02:50","date_gmt":"2018-03-16T16:02:50","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2018\/03\/undoing-aging-with-aubrey-de-grey-part-three"},"modified":"2018-03-16T09:02:50","modified_gmt":"2018-03-16T16:02:50","slug":"undoing-aging-with-aubrey-de-grey-part-three","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2018\/03\/undoing-aging-with-aubrey-de-grey-part-three","title":{"rendered":"Undoing Aging With Aubrey de Grey Part Three"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/undoing-aging-with-aubrey-de-grey-part-three.jpg\"><\/a><\/p>\n<p>Parte 3 of the SENS Research Foundation interview by LEAF is out!<\/p>\n<hr>\n<p>Welcome to part three and the final part of our SENS Undoing Aging 2018 interview; we have a few more scientific questions today for Aubrey and his team as well as questions about future developments and taking new therapies to market.<\/p>\n<p><strong>Dr. de Grey, has your position on the relevance of telomere attrition changed since you first devised SENS, especially in the light of the recent results with fibrosis and your involvement with <a href=\"http:\/\/www.agexinc.com\/\">AgeX<\/a>?<\/strong><\/p>\n<p>Aubrey: No. Let\u2019s start with the big picture. Neither I nor anyone sensible has ever suggested that telomere attrition has no functional effects in aging: telomere attrition causes cells to become senescent and runs down the proliferative capacity of stem cells, amongst other things. Nor have I suggested that there wouldn\u2019t be some short-term health benefits to activating telomerase or telomerase gene therapy in aging animals or animal models of age-related disease (or even their human equivalents). Indeed, there was plenty of animal data to support this long before the recent results with a mouse model of idiopathic pulmonary fibrosis (IPF)[1].<\/p>\n<p><!-- Link: <a href=\"https:\/\/www.leafscience.org\/undoing-aging-with-aubrey-de-grey-part-three\/\">https:\/\/www.leafscience.org\/undoing-aging-with-aubrey-de-grey-part-three\/<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Parte 3 of the SENS Research Foundation interview by LEAF is out! Welcome to part three and the final part of our SENS Undoing Aging 2018 interview; we have a few more scientific questions today for Aubrey and his team as well as questions about future developments and taking new therapies to market. Dr. de [\u2026]<\/p>\n","protected":false},"author":418,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269],"tags":[],"class_list":["post-76947","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/76947","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/418"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=76947"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/76947\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=76947"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=76947"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=76947"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}