{"id":76269,"date":"2018-02-23T15:02:39","date_gmt":"2018-02-23T23:02:39","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2018\/02\/enzyme-designed-entirely-from-scratch-opens-a-world-of-biological-possibility"},"modified":"2018-02-25T11:05:24","modified_gmt":"2018-02-25T19:05:24","slug":"enzyme-designed-entirely-from-scratch-opens-a-world-of-biological-possibility","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2018\/02\/enzyme-designed-entirely-from-scratch-opens-a-world-of-biological-possibility","title":{"rendered":"Enzyme Designed Entirely From Scratch Opens a World of Biological Possibility"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/enzyme-designed-entirely-from-scratch-opens-a-world-of-biological-possibility.jpg\"><\/a><\/p>\n<p>Ann Donnelly was utterly confused the first time she examined her protein. On all counts, it behaved like an enzyme\u2014a protein catalyst that speeds up biological reactions in cells. One could argue that enzymes, sculpted by eons of evolution, make life possible.<\/p>\n<p>There was just one problem: her protein wasn\u2019t evolved. It wasn\u2019t even \u201cnatural.\u201d It was, in fact, a completely artificial construct made with random sequences of DNA\u2014something that\u2019s never existed in nature before.<\/p>\n<p>Donnelly was looking at the first artificial enzyme. An artificial protein that, by all accounts, should not be able to play nice with the intricate web of biochemical components and reactions that support life.<\/p>\n<p><!-- Link: <a href=\"https:\/\/singularityhub.com\/2018\/01\/31\/enzyme-designed-entirely-from-scratch-opens-a-world-of-biological-possibility\/#sm.00001laeh59ookfduq2gn7n40l7dr\">https:\/\/singularityhub.com\/2018\/01\/31\/enzyme-designed-entire...gn7n40l7dr<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ann Donnelly was utterly confused the first time she examined her protein. On all counts, it behaved like an enzyme\u2014a protein catalyst that speeds up biological reactions in cells. One could argue that enzymes, sculpted by eons of evolution, make life possible. There was just one problem: her protein wasn\u2019t evolved. It wasn\u2019t even \u201cnatural.\u201d [\u2026]<\/p>\n","protected":false},"author":388,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,385],"tags":[],"class_list":["post-76269","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-evolution"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/76269","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/388"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=76269"}],"version-history":[{"count":1,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/76269\/revisions"}],"predecessor-version":[{"id":76338,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/76269\/revisions\/76338"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=76269"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=76269"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=76269"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}