{"id":75526,"date":"2018-01-23T12:02:33","date_gmt":"2018-01-23T20:02:33","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2018\/01\/the-hallmarks-of-aging-deregulated-nutrient-sensing"},"modified":"2018-01-23T12:02:33","modified_gmt":"2018-01-23T20:02:33","slug":"the-hallmarks-of-aging-deregulated-nutrient-sensing","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2018\/01\/the-hallmarks-of-aging-deregulated-nutrient-sensing","title":{"rendered":"The Hallmarks of Aging: Deregulated Nutrient Sensing"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/the-hallmarks-of-aging-deregulated-nutrient-sensing.jpg\"><\/a><\/p>\n<p>As part of our ongoing series covering the hallmarks of aging, we are taking a look at deregulated nutrient sensing today and how these four pathways regulate metabolism and influence aging.<\/p>\n<p>To understand studies on nutrient sensing in the context of aging, let\u2019s introduce four key protein groups. In this post, we\u2019ll explore the pathways they help control and how they affect aging. These key proteins are IGF-1, mTOR, sirtuins, and AMPK[2]. We call these proteins \u201cnutrient sensing\u201d because nutrient levels influence their activity[2].<\/p>\n<p><!-- Link: <a href=\"https:\/\/www.leafscience.org\/the-hallmarks-of-aging-deregulated-nutrient-sensing\/\">https:\/\/www.leafscience.org\/the-hallmarks-of-aging-deregulated-nutrient-sensing\/<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>As part of our ongoing series covering the hallmarks of aging, we are taking a look at deregulated nutrient sensing today and how these four pathways regulate metabolism and influence aging. To understand studies on nutrient sensing in the context of aging, let\u2019s introduce four key protein groups. In this post, we\u2019ll explore the pathways [\u2026]<\/p>\n","protected":false},"author":370,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[269],"tags":[],"class_list":["post-75526","post","type-post","status-publish","format-standard","hentry","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/75526","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/370"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=75526"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/75526\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=75526"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=75526"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=75526"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}