{"id":70762,"date":"2017-07-09T12:42:34","date_gmt":"2017-07-09T19:42:34","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2017\/07\/using-macrophages-to-reverse-atherosclerosis"},"modified":"2017-07-10T12:00:15","modified_gmt":"2017-07-10T19:00:15","slug":"using-macrophages-to-reverse-atherosclerosis","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2017\/07\/using-macrophages-to-reverse-atherosclerosis","title":{"rendered":"Using Macrophages to Reverse Atherosclerosis"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/using-macrophages-to-reverse-atherosclerosis.jpg\"><\/a><\/p>\n<p>Increasing the level of autophagy might be the key to effective treatment of heart disease.<\/p>\n<hr>\n<p>Today we will be looking at a new study that is attempting to treat atherosclerosis, one of the biggest age-related killers globally. As we age, our risk of developing atherosclerosis rises along with related conditions, such as hypertension.<\/p>\n<p>We will be taking a look at new research that has reversed atherosclerosis in mice and is on the road to <a href=\"http:\/\/www.leafscience.org\/clinical-trials\/\">clinical trials<\/a> in the future. Before we do that, let\u2019s talk a little bit about how the disease develops and how macrophages work.<\/p>\n<p><strong>What is Atherosclerosis?<\/strong><\/p>\n<p>Atherosclerosis is an age-related disease where toxic, oxidized cholesterol deposits in the blood stream causes inflammation in the artery wall. This causes <a href=\"http:\/\/www.leafscience.org\/macrophages\/\">macrophages<\/a> to swarm to the toxic cholesterol deposits, and become either M1 inflammatory or M2 healing cell types depending on the signals there.<\/p>\n<p><!-- Link: <a href=\"http:\/\/www.leafscience.org\/atherosclerosis\/\">http:\/\/www.leafscience.org\/atherosclerosis\/<\/a> --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Increasing the level of autophagy might be the key to effective treatment of heart disease. Today we will be looking at a new study that is attempting to treat atherosclerosis, one of the biggest age-related killers globally. As we age, our risk of developing atherosclerosis rises along with related conditions, such as hypertension. We will [\u2026]<\/p>\n","protected":false},"author":370,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269],"tags":[],"class_list":["post-70762","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/70762","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/370"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=70762"}],"version-history":[{"count":1,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/70762\/revisions"}],"predecessor-version":[{"id":70793,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/70762\/revisions\/70793"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=70762"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=70762"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=70762"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}